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Laboratory of Nutritional Chemistry, Department of Food Science and Technology, Faculty of Agriculture, Kyoto University, Kyoto 606-01; and Health Science Laboratory, Nisshin Central Research Institute, Nisshin Food Products Company, Kusatsu, Shiga 525, Japan
Received 5 January 1996; accepted in final form 30 May 1996.
Matsumoto, Keitaro, Kengo Ishihara, Kazunori Tanaka, Kazuo
Inoue, and Tohru Fushiki. An adjustable-current swimming pool for
the evaluation of endurance capacity of mice. J. Appl. Physiol. 81(4): 1843-1849, 1996.
A new
forced-swimming apparatus for determining maximum swimming time in mice
was devised for use in the evaluation of the endurance capacity of Std
ddY and CDF1 mice after various diet and drug treatments. With the
apparatus, a water current is generated by circulating water with a
pump in a swimming pool. A spout and suction slit were contrived to generate a constant current while the strength of the current is
regulated by a valve. The decrease in the leg-kicking intervals of mice
accompanying the increase in the current speed confirmed that the
workload is adjustable by regulation of the current speed. Compared
with the number of forelimb strokes, that of the hindlimb kicks was
greater. The swimming time until fatigue was observed to decrease with
increasing current speed in the two strains of mice. As biochemical
indexes, the blood lactate and muscle glycogen levels corroborated the
correlation between current speed and increase in workload. These
results indicate that the apparatus employed in the present study is
suitable for the evaluation of the endurance capacity of mice and that
it is useful for detecting the effects of dietary differences and drug
pretreatments on this capacity.
forced-swimming system; swimming capacity; work intensity
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