Journal of Applied Physiology Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 81: 1739-1743, 1996;
8750-7587/96 $5.00
This Article
Right arrow Full Text Free
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Fontanari, P.
Right arrow Articles by Jammes, Y.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Fontanari, P.
Right arrow Articles by Jammes, Y.

Journal of Applied Physiology
Vol. 81, No. 4, pp. 1739-1743, October 1996
CONTROL OF BREATHING, CIRCULATION, AND TEMPERATURE

Changes in airway resistance induced by nasal inhalation of cold dry, dry, or moist air in normal individuals

Pierre Fontanari, Henri Burnet, Marie Caroline Zattara-Hartmann, and Yves Jammes

Laboratoire de Physiopathologie Respiratoire Intégrée et Cellulaire, Unité de Recherche Associée, Centre National de la Recherche Scientifique 1630, Institut Jean Roche, Faculté de Médecine, Université de la Méditerrannée, 13916 Marseille cédex 20, France

Received 29 September 1995; accepted in final form 7 May 1996.

Fontanari, Pierre, Henri Burnet, Marie Caroline Zattara-Hartmann, and Yves Jammes. Changes in airway resistance induced by nasal inhalation of cold dry, dry, or moist air in normal individuals. J. Appl. Physiol. 81(4): 1739-1743, 1996.---Nasopulmonary bronchomotor reflexes elicited by mechanical or irritant stimulation of the nose have been described in animals and asthmatic patients. However, few studies were devoted to the consequences of nasal breathing of cold and dry air or of only dry or only moist air on the bronchomotor control in normal individuals. The present study reported changes in interruption resistance (Rint) measured during eupneic breathing of moderately cold (-4 or -10°C) and dry [0.3% relative humidity (RH)] air or of room air at 23°C that is either dry (0.3% RH) or moist (97% RH). Nasal inhalation of cold (-4°C) dry air or of only dry air significantly increased baseline Rint value (17 and 21%, respectively) throughout the 15-min test periods. The response to cold was significantly accentuated when the air temperature was lowered to -10°C (42%). After nasal anesthesia or inhalation of a cholinergic antagonist, cold air did not induce a change in Rint. Nasal inhalation of moist room air had no effect. No Rint changes were measured during oral breathing of the three test agents. It is concluded that the activation of cold receptors or osmoreceptors in the nasal mucosa induces protective bronchoconstrictor responses in normal individuals.

nose; cold receptors; osmoreceptors; bronchomotor control; humans

0161-7567/96 $5.00 Copyright © 1996 the American Physiological Society




This article has been cited by other articles:


Home page
 J. Appl. Physiol.Home page
B. J. Canning
Reflex regulation of airway smooth muscle tone
J Appl Physiol, September 1, 2006; 101(3): 971 - 985.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
M. Thomas, V. S. Kocevar, Q. Zhang, D. D. Yin, and D. Price
Asthma-Related Health Care Resource Use Among Asthmatic Children With and Without Concomitant Allergic Rhinitis
Pediatrics, January 1, 2005; 115(1): 129 - 134.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
W. Chatila, T. Nugent, G. Vance, J. Gaughan, and G. J. Criner
The Effects of High-Flow vs Low-Flow Oxygen on Exercise in Advanced Obstructive Airways Disease
Chest, October 1, 2004; 126(4): 1108 - 1115.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
L. S. ON, P. BOONYONGSUNCHAI, S. WEBB, L. DAVIES, P. M. A. CALVERLEY, and R. W. COSTELLO
Function of Pulmonary Neuronal M2 Muscarinic Receptors in Stable Chronic Obstructive Pulmonary Disease
Am. J. Respir. Crit. Care Med., May 1, 2001; 163(6): 1320 - 1325.
[Abstract] [Full Text]

Home page
 J. Appl. Physiol.Home page
M. L. McLane, J. A. Nelson, K. A. Lenner, R. Hejal, C. Kotaru, M. Skowronski, A. Coreno, E. Lane, and E. R. McFadden Jr.
Integrated response of the upper and lower respiratory tract of asthmatic subjects to frigid air
J Appl Physiol, March 1, 2000; 88(3): 1043 - 1050.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online