Journal of Applied Physiology, Vol 80, Issue 4 1345-1350, Copyright © 1996 by American Physiological Society

ARTICLES

Comparison of muscle near-infrared spectroscopy and femoral blood gases during steady-state exercise in humans

F. Costes, J. C. Barthelemy, L. Feasson, T. Busso, A. Geyssant and C. Denis
Laboratoire de Physiologie-Groupement d'Interet Public Exercice, Faculte de Medecine Jacques Lisfranc, Universite Jean Monnet Saint-Etienne, France.

Near-infrared spectroscopy (NIRS) is a noninvasive way of measuring muscular oxygenation. We evaluated the relationship between NIRS signal [infrared muscle oxygen saturation (IR-SO2mus)] and the femoral venous oxygen saturation (SfvO2) during cycling exercise. Six healthy subjects performed a 30-min steady-state exercise at 80% maximal oxygen uptake in normoxia and hypoxia (inspired O2 fraction = 0.105). IR-So2mus was recorded continuously throughout the tests with the NIRS probe located on the vastus lateralis. During exercise, blood samples were withdrawn every 5 min from radial artery and femoral vein catheters. In normoxia, IR-So2mus initiated a transient nonsignificant decrease at 5 min, then returned to preexercise level, whereas SfvO2 showed a fast decrease, reaching 18% saturation at 10 min without further change. By contrast, in hypoxia, IR-SO2mus and SfvO2 demonstrated a parallel decrease then stabilized at 10 min. We conclude that IR-SO2mus appears to parallel SfvO2 when both the arterial and venous oxygen contents decrease during steady-state exercise in hypoxia, whereas IR-SO2mus does not follow SfvO2 change in normoxia.

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