Journal of Applied Physiology, Vol 74, Issue 6 2687-2693, Copyright © 1993 by American Physiological Society

ARTICLES

Noninvasive cardiac output measurement by arterial pulse analysis compared with inert gas rebreathing

W. J. Stok, F. Baisch, A. Hillebrecht, H. Schulz, M. Meyer and J. M. Karemaker
Department of Physiology, University of Amsterdam Academic Medical Centre, The Netherlands.

Noninvasive cardiac output (CO) measured by arterial pulse analysis was compared with that measured by inert gas rebreathing in six healthy male volunteers. Pulse contour analysis was applied to the pressure wave output of a Finapres, which noninvasively measures continuous arterial pressure in a finger. Data were collected before, during, and after a 10-day 6 degrees head-down tilt experiment. Intravenous saline loading and lower body negative pressure stimuli varied CO over 2.8-9.6 l/min, as measured by the rebreathing technique. Because pulse contour provides only relative changes in CO, to obtain absolute values it must be calibrated against another measurement. Pulse contour data were calibrated every measurement day against the mean of two to four control rebreathing CO measurements before the lower body negative pressure or intravenous saline loading stimuli. Using one averaged calibration factor per subject for a total of 27 days, we compared the results of both methods. The linear regression between pulse contour (Pc CO) and rebreathing CO (Rebr CO) was Pc CO = 0.15 + 0.98(Rebr CO) (r = 0.96). The standard deviation of the difference of the two methods was 0.5 l/min (n = 205), excluding data used for calibration. By monitoring pulse contour CO before and during rebreathing, the rebreathing maneuver itself was shown to produce a substantial increase in CO that was mainly related to an increase in heart rate.(ABSTRACT TRUNCATED AT 250 WORDS)

This article has been cited by other articles:

				M. Zaregarizi, B. Edwards, K. George, Y. Harrison, H. Jones, and G. Atkinson Acute changes in cardiovascular function during the onset period of daytime sleep: comparison to lying awake and standing J Appl Physiol, October 1, 2007; 103(4): 1332 - 1338. [Abstract] [Full Text] [PDF]

				J. Giese-Davis, F. H. Wilhelm, A. Conrad, H. C. Abercrombie, S. Sephton, M. Yutsis, E. Neri, C. B. Taylor, H. C. Kraemer, and D. Spiegel Depression and stress reactivity in metastatic breast cancer. Psychosom Med, September 1, 2006; 68(5): 675 - 683. [Abstract] [Full Text] [PDF]

				J. P. Fisher, S. Ogoh, E. A. Dawson, P. J. Fadel, N. H. Secher, P. B. Raven, and M. J. White Cardiac and vasomotor components of the carotid baroreflex control of arterial blood pressure during isometric exercise in humans J. Physiol., May 1, 2006; 572(3): 869 - 880. [Abstract] [Full Text] [PDF]

				R. Aardenburg, M. E. Spaanderman, H. W. van Eijndhoven, P. W. de Leeuw, and L. L. Peeters Formerly Preeclamptic Women With a Subnormal Plasma Volume Are Unable to Maintain a Rise in Stroke Volume During Moderate Exercise Reproductive Sciences, December 1, 2005; 12(8): 599 - 603. [Abstract] [PDF]

				L. W. J Bogert and J. J van Lieshout Non-invasive pulsatile arterial pressure and stroke volume changes from the human finger Exp Physiol, July 1, 2005; 90(4): 437 - 446. [Abstract] [Full Text] [PDF]

				R. Aardenburg, M. E. Spaanderman, D. A. Courtar, H. W. van Eijndhoven, P. W. de Leeuw, and L. L. Peeters A Subnormal Plasma Volume in Formerly Preeclamptic Women is Associated with a Low Venous Capacitance Reproductive Sciences, February 1, 2005; 12(2): 107 - 111. [Abstract] [PDF]

				N. P. van Orshoven, P. L. Oey, L. J. van Schelven, J. M. M. Roelofs, P. A. F. Jansen, and L. M. A. Akkermans Effect of gastric distension on cardiovascular parameters: gastrovascular reflex is attenuated in the elderly J. Physiol., March 1, 2004; 555(2): 573 - 583. [Abstract] [Full Text] [PDF]

				G. Piccirillo, M. Nocco, A. Moise, M. Lionetti, C. Naso, S. di Carlo, and V. Marigliano Influence of Vitamin C on Baroreflex Sensitivity in Chronic Heart Failure Hypertension, June 1, 2003; 41(6): 1240 - 1245. [Abstract] [Full Text] [PDF]

				P. Grossman, F. H. Wilhelm, I. Kawachi, and D. Sparrow Gender Differences in Psychophysiological Responses to Speech Stress Among Older Social Phobics:: Congruence and Incongruence Between Self-Evaluative and Cardiovascular Reactions Psychosom Med, September 1, 2001; 63(5): 765 - 777. [Abstract] [Full Text] [PDF]

				C. Cerutti, M. P. Gustin, P. Molino, and C. Z. Paultre Beat-to-beat stroke volume estimation from aortic pressure waveform in conscious rats: comparison of models Am J Physiol Heart Circ Physiol, September 1, 2001; 281(3): H1148 - H1155. [Abstract] [Full Text] [PDF]

				M. Girardis, S. Milesi, S. Donato, M. Raffaelli, A. Spasiano, G. Antonutto, A. Pasqualucci, and A. Pasetto The Hemodynamic and Metabolic Effects of Tourniquet Application During Knee Surgery Anesth. Analg., September 1, 2000; 91(3): 727 - 731. [Abstract] [Full Text] [PDF]

				W. J. Stok, R. C. O. Stringer, and J. M. Karemaker Noninvasive cardiac output measurement in orthostasis: pulse contour analysis compared with acetylene rebreathing J Appl Physiol, December 1, 1999; 87(6): 2266 - 2273. [Abstract] [Full Text] [PDF]

				H. L. Ristuccia, P. Grossman, L. L. Watkins, and B. Lown Incremental Bias in Finapres Estimation of Baseline Blood Pressure Levels Over Time Hypertension, April 1, 1997; 29(4): 1039 - 1043. [Abstract] [Full Text]