Journal of Applied Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 74: 1499-1503, 1993;
8750-7587/93 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Brechue, W. F.
Right arrow Articles by Stainsby, W. N.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Brechue, W. F.
Right arrow Articles by Stainsby, W. N.

Journal of Applied Physiology, Vol 74, Issue 4 1499-1503, Copyright © 1993 by American Physiological Society

ARTICLES

Blood flow elevation increases VO2 maximum during repetitive tetanic contractions of dog muscle in situ

W. F. Brechue, B. T. Ameredes, G. M. Andrew and W. N. Stainsby
Department of Physiology, College of Medicine, University of Florida, Gainesville 32610.

Blood flow through the gastrocnemius-plantaris muscle of the dog in situ was increased by a pump in the arterial supply during a 30-min period of 1/s isotonic tetanic contractions. Compared with a control series of experiments with normoxemia and spontaneous flow, the pump increased flow 84%, from 1.51 +/- 0.08 to 2.78 +/- 0.15 ml.g-1.min-1. The perfusion pressure was increased from 125 to 196 mmHg. The pump hyperemia increased maximal O2 uptake (VO2) at 5 min of contractions by 31%, from 8.97 +/- 0.44 to 12.89 +/- 0.30 mumol.g-1.min-1. The extraction was decreased, and venous PO2 (PVO2) was increased. Fatigue, measured as a drop in power production from the highest level at 10 s to 30 min, was 49% during pump hyperemia and 54% in the control conditions. VO2 decreased 30% from the 5-min value to the 30-min value with pump hyperemia and 28% over the same time in the control conditions. At maximal VO2, the ratio VO2/PVO2 was increased by pump hyperemia compared with control conditions, suggesting an increased O2 diffusing conductance of the muscles. We conclude that the elevated perfusion pressure of pump hyperemia increased flow to raise maximal VO2 mainly in areas of the muscle that had restricted flow under control conditions.


This article has been cited by other articles:


Home page
 J. Appl. Physiol.Home page
R. T. Hepple, D. J. Krause, J. L. Hagen, and C. C. Jackson
VO2 max is unaffected by altering the temporal pattern of stimulation frequency in rat hindlimb in situ
J Appl Physiol, August 1, 2003; 95(2): 705 - 711.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
B. T. Ameredes, W. F. Brechue, and W. N. Stainsby
Mechanical and metabolic determination of VO2 and fatigue during repetitive isometric contractions in situ
J Appl Physiol, June 1, 1998; 84(6): 1909 - 1916.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
B. T. Ameredes and M. A. Provenzano
Regional intramuscular pressure development and fatigue in the canine gastrocnemius muscle in situ
J Appl Physiol, December 1, 1997; 83(6): 1867 - 1876.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online