| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Journal of Applied Physiology, Vol 73, Issue 5 1825-1830, Copyright © 1992 by American Physiological Society
ARTICLES |
L. G. Jorgensen, G. Perko and N. H. Secher
Department of Vascular Surgery, Rigshospitalet, University of Copenhagen, Denmark.
Transcranial Doppler ultrasound-determined middle (MCA) and anterior (ACA) cerebral artery mean flow velocities (Vmean) and pulsatility indexes (PI) were measured during "no-load" [21, 60, and 102 revolutions/min (rpm)] and loaded cycling (30, 60, and 149 W) at approximately 60 rpm. At rest Vmean MCA was 51 (36-55) cm/s (median and range; n = 10) and Vmean ACA was 41 (36-49) cm/s (n = 7; P < 0.05). With no load on the cycle Vmean MCA increased 4 (2-36), 10 (0-47), and 27% (4-58) (P < 0.05) at the three pedaling frequencies, respectively; arterial PCO2 (PaCO2) remained constant. During loaded cycling the increases were 19 (6-42), 25 (2-45), and 32% (12-67) (P < 0.01), respectively, with only a minimal change in PaCO2. No significant changes were observed in Vmean ACA. Changes in Vmean MCA were similar to those recorded by the initial slope index (ISI) of the 133Xe clearance method (n = 11), which in turn were smaller than increases recorded by the fast-compartment flow. PI ACA followed PI MCA during no-load as well as loaded exercise and increased with work rate, perhaps reflecting an increase in pulse pressure from 56 (48-63) mmHg at rest to 109 (88-123) mmHg at 149 W (P < 0.01). Data demonstrate a graded increase in regional cerebral perfusion during dynamic exercise corresponding to the MCA territory.
This article has been cited by other articles:
|
|
 |
|
  J. P. Fisher, S. Ogoh, C. N. Young, P. B. Raven, and P. J. Fadel Regulation of middle cerebral artery blood velocity during dynamic exercise in humans: influence of aging J Appl Physiol, July 1, 2008; 105(1): 266 - 273. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. S. Larsen, P. Rasmussen, M. Overgaard, N. H. Secher, and H. B. Nielsen Non-selective {beta}-adrenergic blockade prevents reduction of the cerebral metabolic ratio during exhaustive exercise in humans J. Physiol., June 1, 2008; 586(11): 2807 - 2815. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. H. Secher, T. Seifert, and J. J. Van Lieshout Cerebral blood flow and metabolism during exercise: implications for fatigue J Appl Physiol, January 1, 2008; 104(1): 306 - 314. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y.-S. Kim, R. Krogh-Madsen, P. Rasmussen, P. Plomgaard, S. Ogoh, N. H. Secher, and J. J. van Lieshout Effects of hyperglycemia on the cerebrovascular response to rhythmic handgrip exercise Am J Physiol Heart Circ Physiol, July 1, 2007; 293(1): H467 - H473. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. H. E. Imray, S. D. Myers, K. T. S. Pattinson, A. R. Bradwell, C. W. Chan, S. Harris, P. Collins, A. D. Wright, and the Birmingham Medical Research Expeditionary Soci Effect of exercise on cerebral perfusion in humans at high altitude J Appl Physiol, August 1, 2005; 99(2): 699 - 706. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. K. Dalsgaard, S. Volianitis, C. C. Yoshiga, E. A. Dawson, and N. H. Secher Cerebral metabolism during upper and lower body exercise J Appl Physiol, November 1, 2004; 97(5): 1733 - 1739. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 I. K. Moppett and R. P. Mahajan Transcranial Doppler ultrasonography in anaesthesia and intensive care Br. J. Anaesth., November 1, 2004; 93(5): 710 - 724. [Full Text] [PDF]
|
|
|
|
|
|
M. Brys, C. M. Brown, H. Marthol, R. Franta, and M. J. Hilz Dynamic cerebral autoregulation remains stable during physical challenge in healthy persons Am J Physiol Heart Circ Physiol, August 7, 2003; 285(3): H1048 - H1054. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Jensen, H. B. Nielsen, K. Ide, P. L. Madsen, L. B. Svendsen, U. G. Svendsen, and N. H. Secher Cerebral Oxygenation During Exercise in Patients With Terminal Lung Disease* Chest, August 1, 2002; 122(2): 445 - 450. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. A. Giller, A. M. Giller, C. R. Cooper, and M. R. Hatab Evaluation of the cerebral hemodynamic response to rhythmic handgrip J Appl Physiol, June 1, 2000; 88(6): 2205 - 2213. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. B. Nielsen, R. Boushel, P. Madsen, and N. H. Secher Cerebral desaturation during exercise reversed by O2 supplementation Am J Physiol Heart Circ Physiol, September 1, 1999; 277(3): H1045 - H1052. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. J. Poulin, R. J. Syed, and P. A. Robbins Assessments of flow by transcranial Doppler ultrasound in the middle cerebral artery during exercise in humans J Appl Physiol, May 1, 1999; 86(5): 1632 - 1637. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. Demolis, Y. R. T. Dinh, and J.-F. Giudicelli Relationships Between Cerebral Regional Blood Flow Velocities and Volumetric Blood Flows and Their Respective Reactivities to Acetazolamide Stroke, October 1, 1996; 27(10): 1835 - 1839. [Abstract] [Full Text]
|
|
|
|
|
|
W. A. Kofke, P. Brauer, R. Policare, S. Penthany, D. Barker, and J. Horton Middle Cerebral Artery Blood Flow Velocity and Stable Xenon-Enhanced Computed Tomographic Blood Flow During Balloon Test Occlusion of the Internal Carotid Artery Stroke, September 1, 1995; 26(9): 1603 - 1606. [Abstract] [Full Text]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
