Journal of Applied Physiology AJP: Advances in Physiology Education
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 73: 1190-1195, 1992;
8750-7587/92 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Audi, S. H.
Right arrow Articles by Linehan, J. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Audi, S. H.
Right arrow Articles by Linehan, J. H.

Journal of Applied Physiology, Vol 73, Issue 3 1190-1195, Copyright © 1992 by American Physiological Society

ARTICLES

A method for analysis of pulmonary arterial and venous occlusion data

S. H. Audi, C. A. Dawson and J. H. Linehan
Department of Physiology, Medical College of Wisconsin, Milwaukee 53226.

Recently, we presented a compartmental model of the pulmonary vascular resistance (R) and compliance (C) distribution with the configuration C1R1C2R2C3 (J. Appl. Physiol. 70: 2126-2136, 1991). This model was used to interpret the pressure vs. time data obtained after the sudden occlusion of the arterial inflow (AO), venous outflow (VO), or both inflow and outflow (DO) from an isolated dog lung lobe. In the present study, we present a new approach to the data analysis in terms of this model that is relatively simple to carry out and more robust. The data used to estimate the R's and C's are the steady-state arterial [Pa(0)] and venous [Pv(0)] pressures, the flow rate (Q), the area (A2) encompassed by Pa(t) after AO and the equilibrium pressure (Pd) after DO, and the average slope (m) of the Pa(t) and Pv(t) curves after VO. The following formulas can then be used to calculate the 2 R's and 3 C's: [Pa(0) - Pv(0)]/Q = R1 + R2 = RT, R1C1 congruent to to A2/[Pa(0) - Pd], R1 congruent to [Pa(0) - Pd]/Q, Q/m = C1 + C2 + C3 = CT, and C2 = CT - (RTC1/R2).


This article has been cited by other articles:


Home page
 Am. J. Physiol. Lung Cell. Mol. Physiol.Home page
S. A. Barman
Effect of protein kinase C inhibition on hypoxic pulmonary vasoconstriction
Am J Physiol Lung Cell Mol Physiol, May 1, 2001; 280(5): L888 - L895.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
M. Bousamra II, R. Rossi, E. Jacobs, M. Parviz, C. Busch, L. D. Nelin, S. Haworth, and C. A. Dawson
Systemic lobar shunting induces advanced pulmonary vasculopathy
J. Thorac. Cardiovasc. Surg., July 1, 2000; 120(1): 88 - 98.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Lung Cell. Mol. Physiol.Home page
S. A. Barman
Potassium channels modulate canine pulmonary vasoreactivity to protein kinase C activation
Am J Physiol Lung Cell Mol Physiol, September 1, 1999; 277(3): L558 - L565.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Lung Cell. Mol. Physiol.Home page
S. A. Barman
Potassium channels modulate hypoxic pulmonary vasoconstriction
Am J Physiol Lung Cell Mol Physiol, July 1, 1998; 275(1): L64 - L70.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
R. G. Presson Jr., S. H. Audi, C. C. Hanger, G. M. Zenk, R. A. Sidner, J. H. Linehan, W. W. Wagner Jr., and C. A. Dawson
Anatomic distribution of pulmonary vascular compliance
J Appl Physiol, January 1, 1998; 84(1): 303 - 310.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
S. C. Hillier, J. A. Graham, C. C. Hanger, P. S. Godbey, R. W. Glenny, and W. W. Wagner Jr.
Hypoxic vasoconstriction in pulmonary arterioles and venules
J Appl Physiol, April 1, 1997; 82(4): 1084 - 1090.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online