Journal of Applied Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 73: 240-247, 1992;
8750-7587/92 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Hsia, C. C.
Right arrow Articles by Johnson, R. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hsia, C. C.
Right arrow Articles by Johnson, R. L., Jr

Journal of Applied Physiology, Vol 73, Issue 1 240-247, Copyright © 1992 by American Physiological Society

ARTICLES

Respiratory muscle blood flow in exercising dogs after pneumonectomy

C. C. Hsia, M. Ramanathan, J. L. Pean and R. L. Johnson Jr
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas 75235.

In three foxhounds after left pneumonectomy, the relationships of ventilatory work and respiratory muscle (RM) blood flow to ventilation (VE) during steady-state exercise were examined. VE was measured using a specially constructed respiratory mask and a pneumotach; work of breathing was measured by the esophageal balloon technique. Blood flow to RM was measured by the radionuclide-labeled microsphere technique. Lung compliance after pneumonectomy was 55% of that before pneumonectomy; compliance of the thorax was unchanged. O2 uptake (VO2) of RM comprised only 5% of total body VO2 at exercise. At rest, inspiratory muscles received 62% and expiratory muscles 38% of the total O2 delivered to the RM (QO2RM). During exercise, inspiratory muscles received 59% and expiratory muscles 41% of total QO2RM. Blood flow per gram of muscle to the costal diaphragm was significantly higher than that to the crural diaphragm. The diaphragm, parasternals, and posterior cricoarytenoids were the most important inspiratory muscles, and internal intercostals and external obliques were the most important expiratory muscles for exercise. Up to a VE of 120 l/min through one lung, QO2RM constituted only a small fraction of total body VO2 during exercise and maximal vasodilation in the diaphragm was never approached.


This article has been cited by other articles:


Home page
 J. Appl. Physiol.Home page
C. C. W. Hsia, D. M. Dane, A. S. Estrera, H. E. Wagner, P. D. Wagner, and R. L. Johnson Jr.
Shifting sources of functional limitation following extensive (70%) lung resection
J Appl Physiol, April 1, 2008; 104(4): 1069 - 1079.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
C. C. W. Hsia, S.-I. Takeda, E. Y. Wu, R. W. Glenny, and R. L. Johnson Jr.
Adaptation of respiratory muscle perfusion during exercise to chronically elevated ventilatory work
J Appl Physiol, November 1, 2000; 89(5): 1725 - 1736.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
S.-I. Takeda, M. Ramanathan, A. S. Estrera, and C. C. W. Hsia
Postpneumonectomy alveolar growth does not normalize hemodynamic and mechanical function
J Appl Physiol, August 1, 1999; 87(2): 491 - 497.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online