Journal of Applied Physiology AJP: Regulatory, Integrative and Comparative Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 71: 2206-2210, 1991;
8750-7587/91 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Tipton, C. M.
Right arrow Articles by Williams, S. B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Tipton, C. M.
Right arrow Articles by Williams, S. B.

Journal of Applied Physiology, Vol 71, Issue 6 2206-2210, Copyright © 1991 by American Physiological Society

ARTICLES

Chronic exercise and its hemodynamic influences on resting blood pressure of hypertensive rats

C. M. Tipton, L. A. Sebastian, J. M. Overton, C. R. Woodman and S. B. Williams
Department of Exercise and Sport Sciences, School of Health Related Professions, University of Arizona, Tucson 85721.

Studies with male spontaneously hypertensive rats (SHR) were initiated to determine the hemodynamic relationships associated with the lower resting caudal artery systolic blood pressure (SBP) of endurance-trained SHR populations. After assignment into nontrained (NT, n = 38) and trained (T, n = 38) groups, the T animals were exercised 5 times/wk on a motor-driven treadmill for 12-16 wk at a moderate intensity that ranged from 40 to 70% of their maximum O2 consumption capacity (VO2max). SBP, VO2max, and treadmill run time were determined before the experimental period began and before the animals were instrumented for hemodynamic measurements. At the end of the study, the T rats exhibited significantly lower SBP (NT = 210 +/- 3, T = 200 +/- 3 mmHg) and significantly higher VO2max (NT = 75 +/- 2, T = 83 +/- 2 ml.min-1.kg-1) and run durations (NT = 11.4 +/- 0.4, T = 14.5 +/- 0.3 min). When the animals were anesthetized for insertion of catheters and microprobes for blood pressure and cardiac output (thermodilution) measurements, the T rats had lower values for body mass, heart rate, mean blood pressure, cardiac output, and cardiac index than the NT rats; however, only the body mass and heart rate differences were statistically significant.(ABSTRACT TRUNCATED AT 250 WORDS)


This article has been cited by other articles:


Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
J. M. Kramer, J. A. Beatty, H. R. Little, E. D. Plowey, and T. G. Waldrop
Chronic exercise alters caudal hypothalamic regulation of the cardiovascular system in hypertensive rats
Am J Physiol Regulatory Integrative Comp Physiol, February 1, 2001; 280(2): R389 - R397.
[Abstract] [Full Text] [PDF]

Home page
 HypertensionHome page
N. Niederhoffer, P. Kieffer, D. Desplanches, I. Lartaud-Idjouadiene, M.-H. Sornay, and J. Atkinson
Physical Exercise, Aortic Blood Pressure, and Aortic Wall Elasticity and Composition in Rats
Hypertension, April 1, 2000; 35(4): 919 - 924.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
T. L. Breen, J. Tien, S. R. J. Oliver, T. Hadzic, and G. M. Whitesides
Design and Self-Assembly of Open, Regular, 3D Mesostructures
Science, May 7, 1999; 284(5416): 948 - 951.
[Abstract] [Full Text]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
A. S. Veras-Silva, K. C. Mattos, N. S. Gava, P. C. Brum, C. E. Negrao, and E. M. Krieger
Low-intensity exercise training decreases cardiac output and hypertension in spontaneously hypertensive rats
Am J Physiol Heart Circ Physiol, December 1, 1997; 273(6): H2627 - H2631.
[Abstract] [Full Text] [PDF]

Home page
 HypertensionHome page
G. J. J. Silva, P. C. Brum, C. E. Negrao, and E. M. Krieger
Acute and Chronic Effects of Exercise on Baroreflexes in Spontaneously Hypertensive Rats
Hypertension, September 1, 1997; 30(3): 714 - 719.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online