Journal of Applied Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 71: 1254-1260, 1991;
8750-7587/91 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Daristotle, L.
Right arrow Articles by Bisgard, G. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Daristotle, L.
Right arrow Articles by Bisgard, G. E.

Journal of Applied Physiology, Vol 71, Issue 4 1254-1260, Copyright © 1991 by American Physiological Society

ARTICLES

Ventilatory effects and interactions with change in PaO2 in awake goats

L. Daristotle, M. J. Engwall, W. Z. Niu and G. E. Bisgard
Department of Comparative Biosciences, University of Wisconsin, Madison 53706.

We utilized selective carotid body (CB) perfusion while changing inspired O2 fraction in arterial isocapnia to characterize the non-CB chemoreceptor ventilatory response to changes in arterial PO2 (PaO2) in awake goats and to define the effect of varying levels of CB PO2 on this response. Systemic hyperoxia (PaO2 greater than 400 Torr) significantly increased inspired ventilation (VI) and tidal volume (VT) in goats during CB normoxia, and systemic hypoxia (PaO2 = 29 Torr) significantly increased VI and respiratory frequency in these goats. CB hypoxia (CB PO2 = 34 Torr) in systemic normoxia significantly increased VI, VT, and VT/TI; the ventilatory effects of CB hypoxia were not significantly altered by varying systemic PaO2. We conclude that ventilation is stimulated by systemic hypoxia and hyperoxia in CB normoxia and that this ventilatory response to changes in systemic O2 affects the CB O2 response in an additive manner.


This article has been cited by other articles:


Home page
 J. Appl. Physiol.Home page
P. M. Macey, M. A. Woo, K. E. Macey, T. G. Keens, M. M. Saeed, J. R. Alger, and R. M. Harper
Hypoxia reveals posterior thalamic, cerebellar, midbrain, and limbic deficits in congenital central hypoventilation syndrome
J Appl Physiol, March 1, 2005; 98(3): 958 - 969.
[Abstract] [Full Text] [PDF]

Home page
 Exp PhysiolHome page
A. Vovk, W. D. F Smith, N. D Paterson, D. A Cunningham, and D. H Paterson
Peripheral chemoreceptor control of ventilation following sustained hypoxia in young and older adult humans
Exp Physiol, November 1, 2004; 89(6): 647 - 656.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
S. R. Reeves, E. Gozal, S. Z. Guo, L. R. Sachleben Jr., K. R. Brittian, A. J. Lipton, and D. Gozal
Effect of long-term intermittent and sustained hypoxia on hypoxic ventilatory and metabolic responses in the adult rat
J Appl Physiol, November 1, 2003; 95(5): 1767 - 1774.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
C. Dean, L. K. Geiger, B. M. Sprtel, P. J. Ohtake, and H. V. Forster
An anatomic atlas of the medulla oblongata of the adult goat
J Appl Physiol, September 1, 1999; 87(3): 1220 - 1229.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
H. Gautier, C. Murariu, and M. Bonora
Ventilatory and metabolic responses to ambient hypoxia or hypercapnia in rats exposed to CO hypoxia
J Appl Physiol, July 1, 1997; 83(1): 253 - 261.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online