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J Appl Physiol 67: 1617-1622, 1989;
8750-7587/89 $5.00
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Journal of Applied Physiology, Vol 67, Issue 4 1617-1622, Copyright © 1989 by American Physiological Society

ARTICLES

Effect of helium-oxygen pressure on dopamine detected in vivo in the striatum of hamsters

C. Forni and J. C. Rostain
Unite de Neurochimie, Centre National de la Recherche Scientifique, Marseille, France.

Free-moving hamsters chronically implanted in the striatum with carbon multifiber electrodes selective to dopamine were compressed in a helium-oxygen breathing mixture to 81 bars. Under these conditions, there was an increase in the electrochemical responses recorded from the carbon electrode by differential pulse voltammetry, which occurred during the compression and disappeared when the animals returned to the surface. This change was related to an increase in extracellular dopamine levels induced by the increase in pressure of the helium-oxygen mixture.


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J. C. Rostain, M. C. Gardette-Chauffour, and R. Naquet
EEG and sleep disturbances during dives at 450 msw in helium-nitrogen-oxygen mixture
J Appl Physiol, August 1, 1997; 83(2): 575 - 582.
[Abstract] [Full Text] [PDF]


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