Journal of Applied Physiology AJP: Heart and Circulatory Physiology
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J Appl Physiol 67: 1443-1446, 1989;
8750-7587/89 $5.00
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Journal of Applied Physiology, Vol 67, Issue 4 1443-1446, Copyright © 1989 by American Physiological Society


ARTICLES

Bronchoalveolar lavage in interstitial lung disease: effect of volume of fluid infused

R. A. Helmers, C. S. Dayton, C. Floerchinger and G. W. Hunninghake
Department of Medicine, Veterans Administration, Iowa City, Iowa.

To evaluate the effect of varying infusate volume on the results of bronchoalveolar lavage (BAL) in patients with interstitial lung disease, 55 patients underwent 58 BAL during which both a 100- and 250-ml lavage was performed in the same lobe of the lung. Although the percent of the fluid that was returned and the total numbers of cells were greater in the 250- vs. the 100-ml lavage, there were no significant differences in cell differentials or numbers of cells per milliliter between the 100- and 250-ml BAL. We conclude that infusate volume does not affect cell differentials or numbers of cells per milliliter of bronchoalveolar lavage fluid in patients with interstitial lung disease.





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