Journal of Applied Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 64: 274-284, 1988;
8750-7587/88 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Dawson, C. A.
Right arrow Articles by Rickaby, D. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Dawson, C. A.
Right arrow Articles by Rickaby, D. A.

Journal of Applied Physiology, Vol 64, Issue 1 274-284, Copyright © 1988 by American Physiological Society

ARTICLES

Distributions of vascular pressure and resistance in the lung

C. A. Dawson, T. A. Bronikowski, J. H. Linehan and D. A. Rickaby
Department of Physiology, Medical College of Wisconsin, Milwaukee 53226.

The low-viscosity bolus method was used to determine the longitudinal distributions of vascular resistance and intravascular pressure with respect to cumulative vascular volume from the lobar artery to the lobar vein in isolated dog lung lobes near functional residual capacity under zone 3 conditions. We found that the resistance distribution had two modes, a larger one upstream and a smaller one downstream from a local minimum. Over the range of vascular pressures studied the total vascular resistance decreased and the vascular volume increased with increasing vascular pressure. However, the shape of the normalized resistance distribution was independent of vascular pressure. Comparisons of the resistance distributions with the distributions of arterial, capillary, and venous volumes suggest that the modes represent regions of relatively high resistance proximal and distal to the capillary bed. These results are consistent with the concept that within the lobar vascular bed the highest resistance per unit blood volume is in the smallest arteries and veins, as suggested by morphometric data from other sources.


This article has been cited by other articles:


Home page
 Am. J. Physiol. Lung Cell. Mol. Physiol.Home page
J.-M. Hyvelin, C. O'Connor, and P. McLoughlin
Effect of changes in pH on wall tension in isolated rat pulmonary artery: role of the RhoA/Rho-kinase pathway
Am J Physiol Lung Cell Mol Physiol, October 1, 2004; 287(4): L673 - L684.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
A. H. Stephenson, R. S. Sprague, J. L. Losapio, and A. J. Lonigro
Differential effects of 5,6-EET on segmental pulmonary vasoactivity in the rabbit
Am J Physiol Heart Circ Physiol, June 1, 2003; 284(6): H2153 - H2161.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Lung Cell. Mol. Physiol.Home page
S. A. Barman
Potassium channels modulate canine pulmonary vasoreactivity to protein kinase C activation
Am J Physiol Lung Cell Mol Physiol, September 1, 1999; 277(3): L558 - L565.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Lung Cell. Mol. Physiol.Home page
S. A. Barman
Potassium channels modulate hypoxic pulmonary vasoconstriction
Am J Physiol Lung Cell Mol Physiol, July 1, 1998; 275(1): L64 - L70.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Lung Cell. Mol. Physiol.Home page
C. D. Fike, M. R. Kaplowitz, C. J. Thomas, and L. D. Nelin
Chronic hypoxia decreases nitric oxide production and endothelial nitric oxide synthase in newborn pig lungs
Am J Physiol Lung Cell Mol Physiol, April 1, 1998; 274(4): L517 - L526.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online