| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Journal of Applied Physiology, Vol 63, Issue 6 2388-2395, Copyright © 1987 by American Physiological Society
ARTICLES |
A. R. Coggan and E. F. Coyle
Department of Physical and Health Education, University of Texas, Austin 78712.
Seven cyclists exercised at 70% of maximal O2 uptake (VO2max) until fatigue (170 +/- 9 min) on three occasions, 1 wk apart. During these trials, plasma glucose declined from 5.0 +/- 0.1 to 3.1 +/- 0.1 mM (P less than 0.001) and respiratory exchange ratio (R) fell from 0.87 +/- 0.01 to 0.81 +/- 0.01 (P less than 0.001). After resting 20 min the subjects attempted to continue exercise either 1) after ingesting a placebo, 2) after ingesting glucose polymers (3 g/kg), or 3) when glucose was infused intravenously ("euglycemic clamp"). Placebo ingestion did not restore euglycemia or R. Plasma glucose increased (P less than 0.001) initially to approximately 5 mM and R rose (P less than 0.001) to approximately 0.83 with glucose infusion or carbohydrate ingestion. Plasma glucose and R then fell gradually to 3.9 +/- 0.3 mM and 0.81 +/- 0.01, respectively, after carbohydrate ingestion but were maintained at 5.1 +/- 0.1 mM and 0.83 +/- 0.01, respectively, by glucose infusion. Time to fatigue during this second exercise bout was significantly longer during the carbohydrate ingestion (26 +/- 4 min; P less than 0.05) or glucose infusion (43 +/- 5 min; P less than 0.01) trials compared with the placebo trial (10 +/- 1 min). Plasma insulin (approximately 10 microU/ml) and vastus lateralis muscle glycogen (approximately 40 mmol glucosyl U/kg) did not change during glucose infusion, with three-fourths of total carbohydrate oxidation during the second exercise bout accounted for by the euglycemic glucose infusion rate (1.13 +/- 0.08 g/min).(ABSTRACT TRUNCATED AT 250 WORDS)
This article has been cited by other articles:
|
|
 |
|
  S. E. Yeo, R. L. P. G. Jentjens, G. A. Wallis, and A. E. Jeukendrup Caffeine increases exogenous carbohydrate oxidation during exercise J Appl Physiol, September 1, 2005; 99(3): 844 - 850. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. S. Fulco, K. W. Kambis, A. L. Friedlander, P. B. Rock, S. R. Muza, and A. Cymerman Carbohydrate supplementation improves time-trial cycle performance during energy deficit at 4,300-m altitude J Appl Physiol, September 1, 2005; 99(3): 867 - 876. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A St Clair Gibson and T D Noakes Evidence for complex system integration and dynamic neural regulation of skeletal muscle recruitment during exercise in humans Br. J. Sports Med., December 1, 2004; 38(6): 797 - 806. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. D. Karelis, F. Peronnet, and P. F. Gardiner Insulin does not mediate the attenuation of fatigue associated with glucose infusion in rat plantaris muscle J Appl Physiol, July 1, 2003; 95(1): 330 - 335. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M Perez, A Lucia, A Santalla, and J L Chicharro Effects of electrical stimulation on VO2 kinetics and delta efficiency in healthy young men Br. J. Sports Med., April 1, 2003; 37(2): 140 - 143. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. D. Chinevere, R. D. Sawyer, A. R. Creer, R. K. Conlee, and A. C. Parcell Effects of L-tyrosine and carbohydrate ingestion on endurance exercise performance J Appl Physiol, November 1, 2002; 93(5): 1590 - 1597. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. J. Angus, M. A. Febbraio, and M. Hargreaves Plasma glucose kinetics during prolonged exercise in trained humans when fed carbohydrate Am J Physiol Endocrinol Metab, September 1, 2002; 283(3): E573 - E577. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Jose-Cunilleras, K. W. Hinchcliff, R. A. Sams, S. T. Devor, and J. K. Linderman Glycemic index of a meal fed before exercise alters substrate use and glucose flux in exercising horses J Appl Physiol, January 1, 2002; 92(1): 117 - 128. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. C. Riddell, O. Bar-Or, B. Wilk, M. L. Parolin, and G. J. F. Heigenhauser Substrate utilization during exercise with glucose and glucose plus fructose ingestion in boys ages 10-14 yr J Appl Physiol, March 1, 2001; 90(3): 903 - 911. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. A. Febbraio, A. Chiu, D. J. Angus, M. J. Arkinstall, and J. A. Hawley Effects of carbohydrate ingestion before and during exercise on glucose kinetics and performance J Appl Physiol, December 1, 2000; 89(6): 2220 - 2226. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Kristiansen, J. Gade, J. F. P. Wojtaszewski, B. Kiens, and E. A. Richter Glucose uptake is increased in trained vs. untrained muscle during heavy exercise J Appl Physiol, September 1, 2000; 89(3): 1151 - 1158. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. F Coyle Physical activity as a metabolic stressor Am. J. Clinical Nutrition, August 1, 2000; 72(2): 512S - 520. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. G. Fritzsche, T. W. Switzer, B. J. Hodgkinson, S.-H. Lee, J. C. Martin, and E. F. Coyle Water and carbohydrate ingestion during prolonged exercise increase maximal neuromuscular power J Appl Physiol, February 1, 2000; 88(2): 730 - 737. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. J. Angus, M. Hargreaves, J. Dancey, and M. A. Febbraio Effect of carbohydrate or carbohydrate plus medium-chain triglyceride ingestion on cycling time trial performance J Appl Physiol, January 1, 2000; 88(1): 113 - 119. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. A. Febbraio and J. Dancey Skeletal muscle energy metabolism during prolonged, fatiguing exercise J Appl Physiol, December 1, 1999; 87(6): 2341 - 2347. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. J. C. van Loon, A. E. Jeukendrup, W. H. M. Saris, and A. J. M. Wagenmakers Effect of training status on fuel selection during submaximal exercise with glucose ingestion J Appl Physiol, October 1, 1999; 87(4): 1413 - 1420. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. McConell, R. J. Snow, J. Proietto, and M. Hargreaves Muscle metabolism during prolonged exercise in humans: influence of carbohydrate availability J Appl Physiol, September 1, 1999; 87(3): 1083 - 1086. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Baldwin, R. J. Snow, M. F. Carey, and M. A. Febbraio Muscle IMP accumulation during fatiguing submaximal exercise in endurance trained and untrained men Am J Physiol Regulatory Integrative Comp Physiol, July 1, 1999; 277(1): R295 - R300. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. E. Jeukendrup, A. J. M. Wagenmakers, J. H. C. H. Stegen, A. P. Gijsen, F. Brouns, and W. H. M. Saris Carbohydrate ingestion can completely suppress endogenous glucose production during exercise Am J Physiol Endocrinol Metab, April 1, 1999; 276(4): E672 - E683. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. M. Parkin, M. F. Carey, S. Zhao, and M. A. Febbraio Effect of ambient temperature on human skeletal muscle metabolism during fatiguing submaximal exercise J Appl Physiol, March 1, 1999; 86(3): 902 - 908. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. B. Mitchell, F. X. Pizza, A. Paquet, B. J. Davis, M. B. Forrest, and W. A. Braun Influence of carbohydrate status on immune responses before and after endurance exercise J Appl Physiol, June 1, 1998; 84(6): 1917 - 1925. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. J. Ryan, G. P. Lambert, X. Shi, R. T. Chang, R. W. Summers, and C. V. Gisolfi Effect of hypohydration on gastric emptying and intestinal absorption during exercise J Appl Physiol, May 1, 1998; 84(5): 1581 - 1588. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. P. Kirwan, D. O'Gorman, and W. J. Evans A moderate glycemic meal before endurance exercise can enhance performance J Appl Physiol, January 1, 1998; 84(1): 53 - 59. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. E. Jeukendrup, M. Mensink, W. H. M. Saris, and A. J. M. Wagenmakers Exogenous glucose oxidation during exercise in endurance-trained and untrained subjects J Appl Physiol, March 1, 1997; 82(3): 835 - 840. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Peronnet, Y. Burelle, D. Massicotte, C. Lavoie, and C. Hillaire-Marcel Respective oxidation of 13C-labeled lactate and glucose ingested simultaneously during exercise J Appl Physiol, February 1, 1997; 82(2): 440 - 446. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
