Journal of Applied Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 63: 285-291, 1987;
8750-7587/87 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Armstrong, R. B.
Right arrow Articles by Laughlin, M. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Armstrong, R. B.
Right arrow Articles by Laughlin, M. H.

Journal of Applied Physiology, Vol 63, Issue 1 285-291, Copyright © 1987 by American Physiological Society

ARTICLES

Progressive elevations in muscle blood flow during prolonged exercise in swine

R. B. Armstrong, M. D. Delp, E. F. Goljan and M. H. Laughlin

Distribution of muscle blood flow has not been measured in man during prolonged exercise, but progressive elevations in skin flow coupled with constant cardiac output (QT) have suggested muscle blood flow may be compromised. However, previous experiments with rats demonstrated progressive increases in muscle blood flow over time during prolonged submaximal exercise. The present study was performed to study muscle blood flow in miniature swine during long-term exercise to shed light on this apparent anomaly. QT and distribution of QT were studied with radiolabeled microspheres while pigs ran on a level treadmill at a speed (10.5 km/h) requiring 71 +/- 4% of maximal O2 consumption (VO2 max). QT increased 23% from the 5th to the 30th min of exercise, whereas total skeletal muscle flow increased by 49%. Increases in flow in the muscles resulted from decreased resistance, since mean arterial pressure declined over this time period (-7%). In addition, the proportional increases in muscle flow were similar within synergistic muscle groups independent of fiber type composition (e.g., elbow extensors: 59-78%; elbow flexors: 26-40%). The factor that limited continued exercise appeared to be body temperature. Colonic temperature rose in linear fashion over time; the animals became exhausted at approximately 42 degrees C. These flow data are similar to previous findings in rats and indicate that during prolonged treadmill locomotion in quadrupedal animals muscle blood flow increases over time to near maximal levels.


This article has been cited by other articles:


Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
W.-C. Wu, J. Wang, J. A. Detre, F. W. Wehrli, E. Mohler 3rd, S. J. Ratcliffe, and T. F. Floyd
Hyperemic flow heterogeneity within the calf, foot, and forearm measured with continuous arterial spin labeling MRI
Am J Physiol Heart Circ Physiol, May 1, 2008; 294(5): H2129 - H2136.
[Abstract] [Full Text] [PDF]

Home page
 J. Exp. Biol.Home page
R. L. Marsh and D. J. Ellerby
Partitioning locomotor energy use among and within muscles Muscle blood flow as a measure of muscle oxygen consumption
J. Exp. Biol., July 1, 2006; 209(13): 2385 - 2394.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
J. L. Dobson and L. B. Gladden
Effect of rhythmic tetanic skeletal muscle contractions on peak muscle perfusion
J Appl Physiol, January 1, 2003; 94(1): 11 - 19.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
D. J. Duncker, H. H. Oei, F. Hu, R. Stubenitsky, and P. D. Verdouw
Role of KATP+ channels in regulation of systemic, pulmonary, and coronary vasomotor tone in exercising swine
Am J Physiol Heart Circ Physiol, January 1, 2001; 280(1): H22 - H33.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online