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J Appl Physiol 60: 1446-1450, 1986;
8750-7587/86 $5.00
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Journal of Applied Physiology, Vol 60, Issue 4 1446-1450, Copyright © 1986 by American Physiological Society

ARTICLES

Effects of pressure on uptake and release of calcium by brain synaptosomes

S. C. Gilman, K. K. Kumaroo and J. M. Hallenbeck

Uptake of radioactive calcium from guinea pig brain fractions enriched in synaptosomes could be significantly and reproducibly decreased by exposure to high pressure. Calcium efflux from preloaded synaptosomes was unaffected by pressure exposure. It was hypothesized that the development of pressure-induced encephalopathy may be related to an effect of pressure on the central nervous system calcium transport system.


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A. E. Talpalar and Y. Grossman
Modulation of Rat Corticohippocampal Synaptic Activity by High Pressure and Extracellular Calcium: Single and Frequency Responses
J Neurophysiol, October 1, 2003; 90(4): 2106 - 2114.
[Abstract] [Full Text] [PDF]


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