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J Appl Physiol 59: 1665-1666, 1985;
8750-7587/85 $5.00
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Journal of Applied Physiology, Vol 59, Issue 5 1665-1666, Copyright © 1985 by American Physiological Society

ARTICLES

Implantable device for drug delivery and blood sampling in the rat

J. F. Chester, S. A. Weitzman and R. A. Malt

An implantable drug-delivery and venous sampling device is described that is constructed from a polyvinyl chloride catheter and a rubber intravenous catheter plug coated with Silastic. The implant was used for repeated venous sampling and for both administration of parenteral solutions and injections into the right colon of the rat for periods to 1 mo.




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