Journal of Applied Physiology  AJP: Regulatory, Integrative and Comparative Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
 QUICK SEARCH:   [advanced]


     


J Appl Physiol 57: 528-535, 1984;
8750-7587/84 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Issa, F. G.
Right arrow Articles by Sullivan, C. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Issa, F. G.
Right arrow Articles by Sullivan, C. E.

Journal of Applied Physiology, Vol 57, Issue 2 528-535, Copyright © 1984 by American Physiological Society


ARTICLES

Upper airway closing pressures in snorers

F. G. Issa and C. E. Sullivan

We studied 14 subjects who were selected to represent the broad range of severity of snoring: group A, four subjects who gave a history of snoring only when provoked by nasal obstruction or alcohol intake; group B, six subjects who typically snored for long periods each night; and group C, four subjects who snored heavily all night and who typically experienced a few episodes of obstructive apnea (mean apnea index 4 apneas/h). Low levels of nasal continuous positive airway pressure (CPAP) (range, 2.0-6.0 cmH2O; mean, 4.0 cmH2O) prevented snoring. Nasal occlusion caused upper airway closure during inspiratory efforts in all 14 subjects. There was a relationship between the clinical severity of snoring and the upper airway closing pressure (UACP). Upper airway closure occurred at greater suction pressures in group A than in group C but there was overlap between the three categories. The upper airway was consistently more collapsible in rapid-eye-movement sleep than in non-rapid-eye-movement sleep. There was little evidence of breath-by-breath improvement of upper airway stability during sustained asphyxia, the UACP remaining constant despite marked increases in drive to the diaphragm. In five subjects UACP was measured following alcohol intake. Alcohol reduced upper airway stability in all subjects in a dose-dependent manner.


This article has been cited by other articles:


Home page
ChestHome page
M. Svensson, E. Lindberg, T. Naessen, and C. Janson
Risk factors associated with snoring in women with special emphasis on body mass index: a population-based study.
Chest, April 1, 2006; 129(4): 933 - 941.
[Abstract] [Full Text] [PDF]


Home page
ChestHome page
Y. Huang, D. P. White, and A. Malhotra
The Impact of Anatomic Manipulations on Pharyngeal Collapse: Results From a Computational Model of the Normal Human Upper Airway
Chest, September 1, 2005; 128(3): 1324 - 1330.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Respir. Crit. Care Med.Home page
S. P. Patil, N. M. Punjabi, H. Schneider, C. P. O'Donnell, P. L. Smith, and A. R. Schwartz
A Simplified Method for Measuring Critical Pressures during Sleep in the Clinical Setting
Am. J. Respir. Crit. Care Med., July 1, 2004; 170(1): 86 - 93.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Respir. Crit. Care Med.Home page
A. T Ng, H. Gotsopoulos, J. Qian, and P. A Cistulli
Effect of Oral Appliance Therapy on Upper Airway Collapsibility in Obstructive Sleep Apnea
Am. J. Respir. Crit. Care Med., July 15, 2003; 168(2): 238 - 241.
[Abstract] [Full Text] [PDF]


Home page
Eur Respir JHome page
F.J. O'Donoghue, P.G. Catcheside, E.E. Ellis, R.R. Grunstein, R.J. Pierce, L.S. Rowland, E.R. Collins, S.E. Rochford, and R.D. McEvoy
Sleep hypoventilation in hypercapnic chronic obstructive pulmonary disease: prevalence and associated factors
Eur. Respir. J., June 1, 2003; 21(6): 977 - 984.
[Abstract] [Full Text] [PDF]


Home page
ChestHome page
O. Marrone, G. Insalaco, M. R. Bonsignore, S. Romano, A. Salvaggio, and G. Bonsignore
Sleep Structure Correlates of Continuous Positive Airway Pressure Variations During Application of an Autotitrating Continuous Positive Airway Pressure Machine in Patients With Obstructive Sleep Apnea Syndrome
Chest, March 1, 2002; 121(3): 759 - 767.
[Abstract] [Full Text] [PDF]


Home page
Psychosom. Med.Home page
W. A. Bardwell, S. Ancoli-Israel, C. C. Berry, and J. E. Dimsdale
Neuropsychological Effects of One-Week Continuous Positive Airway Pressure Treatment in Patients With Obstructive Sleep Apnea: A Placebo-Controlled Study
Psychosom Med, July 1, 2001; 63(4): 579 - 584.
[Abstract] [Full Text] [PDF]


Home page
ChestHome page
T. Aittokallio, T. Saaresranta, P. Polo-Kantola, O. Nevalainen, and O. Polo
Analysis of Inspiratory Flow Shapes in Patients With Partial Upper-Airway Obstruction During Sleep
Chest, January 1, 2001; 119(1): 37 - 44.
[Abstract] [Full Text] [PDF]


Home page
J. Appl. Physiol.Home page
G. Pillar, A. Malhotra, R. B. Fogel, J. Beauregard, D. I. Slamowitz, S. A. Shea, and D. P. White
Upper airway muscle responsiveness to rising PCO2 during NREM sleep
J Appl Physiol, October 1, 2000; 89(4): 1275 - 1282.
[Abstract] [Full Text] [PDF]


Home page
ChestHome page
J. S. Loredo, S. Ancoli-Israel, and J. E. Dimsdale
Effect of Continuous Positive Airway Pressure vs Placebo Continuous Positive Airway Pressure on Sleep Quality in Obstructive Sleep Apnea*
Chest, December 1, 1999; 116(6): 1545 - 1549.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Respir. Crit. Care Med.Home page
F. SÉRIÈS, A. DEMOULE, I. MARC, C. SANFAÇON, J. P. DERENNE, and T. SIMILOWSKI
Inspiratory Flow Dynamics During Phrenic Nerve Stimulation in Awake Normals During Nasal Breathing
Am. J. Respir. Crit. Care Med., August 1, 1999; 160(2): 614 - 620.
[Abstract] [Full Text]


Home page
Am. J. Respir. Crit. Care Med.Home page
E. SFORZA, C. PETIAU, T. WEISS, A. THIBAULT, and J. KRIEGER
Pharyngeal Critical Pressure in Patients with Obstructive Sleep Apnea Syndrome . Clinical Implications
Am. J. Respir. Crit. Care Med., January 1, 1999; 159(1): 149 - 157.
[Abstract] [Full Text]


Home page
Am. J. Respir. Crit. Care Med.Home page
M. J. MORRELL, Y. ARABI, B. ZAHN, and M. S. BADR
Progressive Retropalatal Narrowing Preceding Obstructive Apnea
Am. J. Respir. Crit. Care Med., December 1, 1998; 158(6): 1974 - 1981.
[Abstract] [Full Text] [PDF]


Home page
J. Appl. Physiol.Home page
K. G. Henke
Upper airway muscle activity and upper airway resistance in young adults during sleep
J Appl Physiol, February 1, 1998; 84(2): 486 - 491.
[Abstract] [Full Text] [PDF]




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online