| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Journal of Applied Physiology, Vol 57, Issue 1 44-51, Copyright © 1984 by American Physiological Society
ARTICLES |
S. Field, S. Sanci and A. Grassino
The O2 consumption of the respiratory muscles (VO2resp), work of breathing, and the time integral of the transdiaphragmatic pressure (TTdi) were measured in four normal subjects breathing against inspiratory resistance. A total of 39 runs were performed at mean tidal transdiaphragmatic pressures (Pdi) ranging from 15 to 53 cmH2O, respiratory frequencies from 3.5 to 22 breaths/min, and inspiratory time durations (TI) from 32 to 76% of the total breath duration. Each run was maintained from 8 to 17 min and the above parameters were kept constant by the subject via visual feedback of Pdi and TI with an oscilloscope. Most of the runs (36 of 39) were performed at TTdi values below those known to produce respiratory muscle fatigue. We found a strong linear correlation between the VO2resp and the TTdi (r = 0.74, P less than 0.001) and a weaker correlation between VO2resp and W (r = 0.31, P less than 0.05). These data suggest that TTdi is a good estimator of VO2resp over a wide range of respiratory patterns during inspiratory resistance breathing. The high variability seen in respiratory muscle efficiency during resistive breathing may be due to W not being a good indicator of the energy consumed by the respiratory muscles.
This article has been cited by other articles:
|
|
 |
|
  K. E. Finucane, J. A. Panizza, and B. Singh Efficiency of the normal human diaphragm with hyperinflation J Appl Physiol, October 1, 2005; 99(4): 1402 - 1411. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Jubran, B. J. B. Grant, F. Laghi, S. Parthasarathy, and M. J. Tobin Weaning Prediction: Esophageal Pressure Monitoring Complements Readiness Testing Am. J. Respir. Crit. Care Med., June 1, 2005; 171(11): 1252 - 1259. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W D C Man, N Mustfa, D Nikoletou, S Kaul, N Hart, G F Rafferty, N Donaldson, M I Polkey, and J Moxham Effect of salmeterol on respiratory muscle activity during exercise in poorly reversible COPD Thorax, June 1, 2004; 59(6): 471 - 476. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. S. Krupnick, J. Zhu, T. Nguyen, D. Kreisel, K. R. Balsara, E. B. Lankford, C. C. Clark, S. Levine, H. H. Stedman, and J. B. Shrager Inspiratory loading does not accelerate dystrophy in mdx mouse diaphragm: implications for regenerative therapy J Appl Physiol, February 1, 2003; 94(2): 411 - 419. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 O. Diaz, P. Begin, B. Torrealba, E. Jover, and C. Lisboa Effects of noninvasive ventilation on lung hyperinflation in stable hypercapnic COPD Eur. Respir. J., December 1, 2002; 20(6): 1490 - 1498. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
ATS/ERS Statement on Respiratory Muscle Testing Am. J. Respir. Crit. Care Med., August 15, 2002; 166(4): 518 - 624. [Full Text] [PDF]
|
|
|
|
|
|
V. Moscovici da Cruz, S.E. Demarzo, J.B.B. Sobrinho, M.B.P. Amato, L.P. Kowalski, and D. Deheinzelin Effects of tracheotomy on respiratory mechanics in spontaneously breathing patients Eur. Respir. J., July 1, 2002; 20(1): 112 - 117. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Vanpee, C. El Khawand, L. Rousseau, J. Jamart, and L. Delaunois Effects of Nasal Pressure Support on Ventilation and Inspiratory Work in Normocapnic and Hypercapnic Patients With Stable COPD* Chest, July 1, 2002; 122(1): 75 - 83. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. FAUROUX, J. PIGEOT, M. I. POLKEY, G. ROGER, M. BOULE, A. CLEMENT, and F. LOFASO Chronic Stridor Caused by Laryngomalacia in Children . Work of Breathing and Effects of Noninvasive Ventilatory Assistance Am. J. Respir. Crit. Care Med., November 15, 2001; 164(10): 1874 - 1878. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. GORINI, A. CORRADO, G. VILLELLA, R. GINANNI, A. AUGUSTYNEN, and D. TOZZI Physiologic Effects of Negative Pressure Ventilation in Acute Exacerbation of Chronic Obstructive Pulmonary Disease Am. J. Respir. Crit. Care Med., June 1, 2001; 163(7): 1614 - 1618. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Vitacca, S. Nava, M. Confalonieri, L. Bianchi, R. Porta, E. Clini, and N. Ambrosino The Appropriate Setting of Noninvasive Pressure Support Ventilation in Stable COPD Patients Chest, November 1, 2000; 118(5): 1286 - 1293. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Knafelc and P. W. Davenport Relationship between magnitude estimation of resistive loads, inspiratory pressures, and the RREP P1 peak J Appl Physiol, August 1, 1999; 87(2): 516 - 522. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. APPENDINI, A. PURRO, M. GUDJONSDOTTIR, P. BADERNA, A. PATESSIO, S. ZANABONI, C. F. DONNER, and A. ROSSI Physiologic Response of Ventilator-dependent Patients with Chronic Obstructive Pulmonary Disease to Proportional Assist Ventilation and Continuous Positive Airway Pressure Am. J. Respir. Crit. Care Med., May 1, 1999; 159(5): 1510 - 1517. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Yan and J. H. T. Bates Breathing responses to small inspiratory threshold loads in humans J Appl Physiol, March 1, 1999; 86(3): 874 - 880. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. LAGHI, A. JUBRAN, A. TOPELI, P. J. FAHEY, E. R. GARRITY Jr., J. M. ARCIDI, D. J. de PINTO, L. C. EDWARDS, and M. J. TOBIN Effect of Lung Volume Reduction Surgery on Neuromechanical Coupling of the Diaphragm Am. J. Respir. Crit. Care Med., February 1, 1997; 157(2): 475 - 483. [Abstract] [Full Text]
|
|
|
|
 |
|
 K.E. Otte, P. Ahlburg, F. D'Amore, and M. Stellfeld Nutritional Repletion in Malnourished Patients with Emphysema JPEN J Parenter Enteral Nutr, March 1, 1989; 13(2): 152 - 156. [Abstract] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
