Journal of Applied Physiology Information on EB 2010
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 56: 57-63, 1984;
8750-7587/84 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Gleim, G. W.
Right arrow Articles by Nicholas, J. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Gleim, G. W.
Right arrow Articles by Nicholas, J. A.

Journal of Applied Physiology, Vol 56, Issue 1 57-63, Copyright © 1984 by American Physiological Society

ARTICLES

Plasma osmolality, volume, and renin activity at the "anaerobic threshold"

G. W. Gleim, P. M. Zabetakis, E. E. DePasquale, M. F. Michelis and J. A. Nicholas

Plasma renin activity (PRA), volume (PV), osmolality, and hemodynamic parameters were examined in relation to the anaerobic threshold (AT) during progressive cycle ergometry (PE) and repetitive bouts of unilateral isokinetic knee extension-flexion (LE) at 50% maximum voluntary contractions in eight normotensive males. During PE, the observed rise in PRA paralleled that of lactate with abrupt increases occurring at the AT. Correlation of % delta lactate (La), % delta osmolality, and % delta PV with % delta PRA were r = 0.65, 0.36, and -0.51, respectively (all P less than 0.01). In addition, when mean arterial pressure was plotted as a function of VO2, the rate of rise was greater below the AT than above the AT (11.5 vs. -2.4 mmHg X l-1 X min, P less than 0.001). A time control study (TC) exercising subjects for the same duration but at work rates maintained below the AT resulted in significantly lower values for both PRA and La (7.18 vs. 11.27 mg angiotensin I (ANG I) X ml-1 X min and 3.16 vs. 9.93 mM, P less than 0.05 for TC vs. PE) while producing a similar fall in % delta PV and rise in osmolality. During LE, a high correlation was obtained for % delta PRA and % delta La (r = 0.86, P less than 0.01) but not for % delta PRA with % delta PV or % delta osmolality. The data demonstrate that PRA parallels lactate during exercise and that mean arterial pressure rises more slowly beyond the AT despite a more rapid rise in PRA.


This article has been cited by other articles:


Home page
 HeartHome page
M Morikawa, H Sato, H Sato, Y Koretsune, Y Ohnishi, T Kurotobi, T Kuzuya, and M Hori
Sustained left ventricular diastolic dysfunction after exercise in patients with dilated cardiomyopathy
Heart, September 1, 1998; 80(3): 263 - 269.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online