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J Appl Physiol 56: 129-132, 1984;
8750-7587/84 $5.00
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Journal of Applied Physiology, Vol 56, Issue 1 129-132, Copyright © 1984 by American Physiological Society

ARTICLES

Threshold of airway response to inhaled methacholine in healthy men and women

N. Zamel

Threshold of airway response to inhaled methacholine was determined using maximum expiratory partial flow-volume curves in 21 men and 36 women with similar age distribution, all of them healthy nonsmokers. Mean threshold was on average 1.3 doubling dose lower in women than men. There were no sex differences in the increase of maximum expiratory flows after a full inspiration when the airways were constricted by methacholine.


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N. Scichilone, M. Messina, S. Battaglia, F. Catalano, and V. Bellia
Airway hyperresponsiveness in the elderly: prevalence and clinical implications
Eur. Respir. J., February 1, 2005; 25(2): 364 - 375.
[Abstract] [Full Text] [PDF]


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