Journal of Applied Physiology, Vol 55, Issue 2 518-521, Copyright © 1983 by American Physiological Society

ARTICLES

Metabolism of rats running up and down an incline

R. B. Armstrong, M. H. Laughlin, L. Rome and C. R. Taylor

The purpose of these experiments was to determine oxygen consumption (VO2) in rats as a function of treadmill speed (10, 20, 30, 40, and 50 m . min-1) as they ran on the level and up and down a 16 degree (17.8%) incline. The slopes of the regression lines relating VO2 (ml O2 . kg-1 . min-1) to running speed (m . min-1) were linear for all three inclines. The regression slope for uphill runners (y = 1.25x + 47.7) was greater than the regression slopes for level (y = 0.88x + 41.2) (P less than 0.025) or downhill (y = 0.68x + 39.7) (P less than 0.005) runners, and the regression slope for level runners was greater than that for downhill runners (P less than 0.10). All VO2 measurements were submaximal. In conclusion, incline has a significant effect on the metabolism of rats running on a motor-driven treadmill.

This article has been cited by other articles:

				D. Leosco, G. Rengo, G. Iaccarino, A. Filippelli, A. Lymperopoulos, C. Zincarelli, F. Fortunato, L. Golino, M. Marchese, G. Esposito, et al. Exercise training and beta-blocker treatment ameliorate age-dependent impairment of beta-adrenergic receptor signaling and enhance cardiac responsiveness to adrenergic stimulation Am J Physiol Heart Circ Physiol, September 1, 2007; 293(3): H1596 - H1603. [Abstract] [Full Text] [PDF]

				D. Leosco, G. Rengo, G. Iaccarino, E. Sanzari, L. Golino, G. D. Lisa, C. Zincarelli, F. Fortunato, M. Ciccarelli, V. Cimini, et al. Prior Exercise Improves Age-Dependent Vascular Endothelial Growth Factor Downregulation and Angiogenesis Responses to Hind-Limb Ischemia in Old Rats J. Gerontol. A Biol. Sci. Med. Sci., May 1, 2007; 62(5): 471 - 480. [Abstract] [Full Text] [PDF]

				P. J. Mueller Exercise training attenuates increases in lumbar sympathetic nerve activity produced by stimulation of the rostral ventrolateral medulla J Appl Physiol, February 1, 2007; 102(2): 803 - 813. [Abstract] [Full Text] [PDF]

				A Jafari, M A Hosseinpourfaizi, M Houshmand, and A A Ravasi Effect of aerobic exercise training on mtDNA deletion in soleus muscle of trained and untrained Wistar rats Br. J. Sports Med., August 1, 2005; 39(8): 517 - 520. [Abstract] [Full Text] [PDF]

				G. B. Gillis and A. A. Biewener Effects of surface grade on proximal hindlimb muscle strain and activation during rat locomotion J Appl Physiol, November 1, 2002; 93(5): 1731 - 1743. [Abstract] [Full Text] [PDF]

				D. A. Brenner, C. S. Apstein, and K. W. Saupe Exercise Training Attenuates Age-Associated Diastolic Dysfunction in Rats Circulation, July 10, 2001; 104(2): 221 - 226. [Abstract] [Full Text] [PDF]

				Y. Chen, R. C. Serfass, S. M. Mackey-Bojack, K. L. Kelly, J. L. Titus, and F. S. Apple Cardiac troponin T alterations in myocardium and serum of rats after stressful, prolonged intense exercise J Appl Physiol, May 1, 2000; 88(5): 1749 - 1755. [Abstract] [Full Text] [PDF]

				M. D. Delp, C. Duan, C. A. Ray, and R. B. Armstrong Rat hindlimb muscle blood flow during level and downhill locomotion J Appl Physiol, February 1, 1999; 86(2): 564 - 568. [Abstract] [Full Text] [PDF]

				C. L. Carlson and W. W. Winder Liver AMP-activated protein kinase and acetyl-CoA carboxylase during and after exercise J Appl Physiol, February 1, 1999; 86(2): 669 - 674. [Abstract] [Full Text] [PDF]

				J. W. Helge, K. Ayre, S. Chaunchaiyakul, A. J. Hulbert, B. Kiens, and L. H. Storlien Endurance in high-fat-fed rats: effects of carbohydrate content and fatty acid profile J Appl Physiol, October 1, 1998; 85(4): 1342 - 1348. [Abstract] [Full Text] [PDF]

				C. A. Hutber, B. B. Rasmussen, and W. W. Winder Endurance training attenuates the decrease in skeletal muscle malonyl-CoA with exercise J Appl Physiol, December 1, 1997; 83(6): 1917 - 1922. [Abstract] [Full Text] [PDF]

				S. A. Bloomfield, B. E. Girten, and S. E. Weisbrode Effects of vigorous exercise training and beta -agonist administration on bone response to hindlimb suspension J Appl Physiol, July 1, 1997; 83(1): 172 - 178. [Abstract] [Full Text] [PDF]