Journal of Applied Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 55: 139-145, 1983;
8750-7587/83 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Doubt, T. J.
Right arrow Articles by Evans, D. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Doubt, T. J.
Right arrow Articles by Evans, D. E.

Journal of Applied Physiology, Vol 55, Issue 1 139-145, Copyright © 1983 by American Physiological Society

ARTICLES

Effects of hyperbaric oxygen exposure at 31.3 ATA on spontaneously beating cat hearts

T. J. Doubt and D. E. Evans

Cardiovascular responses to raised ambient pressure and acute hyperbaric oxygen (HBO) exposure [HBO, partial pressure of oxygen (PO2) = 2 ATA)] were examined in anesthetized cats. Relatively normoxic [PO2 = 0.35 ATA] helium compression to 31.3 ATA decreased spontaneous heart rate, prolonged the P-R and Q-T intervals of the ECG independently of changes in rate, and significantly increased ventricular contractility. HBO while at depth produced further decreases in heart rate, with no change in the P-R interval. The Q-T interval decreased significantly in the presence of bradycardia, particularly during the first 15 min of exposure. During the first 10-15 min of HBO exposure myocardial contractility and developed ventricular pressure were reduced, but contractility increased significantly at 30 min. These results indicate that HBO interacts with depth effects to produce hyperbaric bradycardia but reverses pressure actions on ventricular repolarization. The inotropic effects of HBO are time dependent, with slightly negative effects occurring initially, followed by positive inotropic actions at 30 min.


This article has been cited by other articles:


Home page
 J. Appl. Physiol.Home page
D. K. Mulkey, R. A. Henderson III, R. W. Putnam, and J. B. Dean
Pressure (4 ATA) increases membrane conductance and firing rate in the rat solitary complex</STRONG><BR> J Appl Physiol, September 1, 2003; 95(3): 922 - 930. <BR> <A HREF=[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online