Journal of Applied Physiology Information on EB 2010
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 52: 949-954, 1982;
8750-7587/82 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Rodenstein, D. O.
Right arrow Articles by Francis, C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Rodenstein, D. O.
Right arrow Articles by Francis, C.

Journal of Applied Physiology, Vol 52, Issue 4 949-954, Copyright © 1982 by American Physiological Society

ARTICLES

Demonstration of failure of body plethysmography in airway obstruction

D. O. Rodenstein, D. C. Stanescu and C. Francis

To demonstrate the role of extrathoracic airways in the overestimation of lung volumes by body plethysmography in airway obstruction, we induced in six normal subjects an artificial airway stenosis by inflating a balloon in the lower trachea. We measured thoracic gas volume in a body plethysmograph simultaneously from mouth pressure (Pm) vs. plethysmographic volume (Vbox) (TGVm) and from esophageal pressure (Pes) vs. Vbox (TGVes). During control measurements there was no difference between TGVm and TGVes (P greater than 0.1) in any subject. Balloon inflation (B) resulted in a significant (P less than 0.01) decrease of specific airway conductance (sGaw) from a mean value of 0.199 +/- 0.66 (SD) to 0.025 +/- 0.01 cmH2O-1 . s-1. TGVm significantly (P less than 0.02) exceeded TGVes in every subject (mean diff 1.24 +/- 0.56 liters) and Pm lagged behind Pes. In two subjects studied at different levels of airway obstruction we found a significant (P less than 0.05) correlation between TGVm-TGVes difference and sGaw. Bypassing the extrathoracic airways by a cuffed endotracheal tube resulted in each case in a degree of airway obstruction comparable to that during balloon inflation (sGaw 0.019 +/- 0.004 cmH2O-1 . s-1), but no difference between TGVm and TGVes (P greater than 0.1). We conclude that lung volume is overestimated by plethysmography in airway obstruction. The overestimation is due to the presence of a compliant extrathoracic airway, and it probably depends on both the degree of airway obstruction and the value of compliance of the extrathoracic airway.


This article has been cited by other articles:


Home page
 Eur Respir JHome page
D. Stanescu
Lung volume measurements
Eur. Respir. J., August 1, 2008; 32(2): 527 - 527.
[Full Text] [PDF]

Home page
 Eur Respir JHome page
M. Cazzola, V. Brusasco, and F. J. Martinez
From the authors
Eur. Respir. J., August 1, 2008; 32(2): 528 - 528.
[Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
D. C Stanescu

J Appl Physiol, December 1, 2006; 101(6): 1812 - 1812.
[Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
T. Z. Janosi, A. Adamicza, G. R. Zosky, T. Asztalos, P. D. Sly, and Z. Hantos
Plethysmographic estimation of thoracic gas volume in apneic mice
J Appl Physiol, August 1, 2006; 101(2): 454 - 459.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
B. J. Dykstra, P. D. Scanlon, M. M. Kester, K. C. Beck, and P. L. Enright
Lung Volumes in 4,774 Patients With Obstructive Lung Disease
Chest, January 1, 1999; 115(1): 68 - 74.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online