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J Appl Physiol 52: 832-837, 1982;
8750-7587/82 $5.00
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Journal of Applied Physiology, Vol 52, Issue 4 832-837, Copyright © 1982 by American Physiological Society

ARTICLES

Respiratory mechanics of a small carnivore: the ferret

A. Vinegar, E. E. Sinnett and P. C. Kosch

The ferret, Mustela putorius furo, is a small relatively inexpensive carnivore with minimal housing requirements. Measurements were made from anesthetized tracheotomized supine males. Values obtained during tidal breathing for six animals (576 +/- 12 g) were as follows: tidal volume, 6.06 +/- 0.30 ml; respiratory frequency, 26.7 +/- 3.9 breaths min-1; dynamic lung compliance, 2.48 +/- 0.21 ml cmH2O-1; pulmonary resistance, 22.56 +/- 1.61 cmH2O . l-1 . s. Pressure-volume curves from nine ferrets revealed almost infinitely compliant chest walls so that lung and total respiratory system curves were essentially the same. Total lung capacity (TLC, 89 +/- 5 ml) and functional residual capacity (17.8 +/- 2.0 ml) were determined by gas freeing the lungs in vivo. The TLC of these ferrets is about the same as in 2.5-kg rabbits. Maximum expiratory flow-volume curves showed peak flows of 10.1 vital capacities (VC) . s-1 at 75% VC and flows of 8.4 and 5.4 VC . s-1 at 50 and 25% VC.


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 International Journal of ToxicologyHome page
S. C. Gad
Pigs and Ferrets as Models in Toxicology and Biological Safety Assessment
International Journal of Toxicology, May 1, 2000; 19(3): 149 - 168.
[Abstract] [PDF]


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