Journal of Applied Physiology Watch the video to learn how APS reaches out to developing nations.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 52: 1000-1007, 1982;
8750-7587/82 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Lai-Fook, S. J.
Right arrow Articles by Kallok, M. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lai-Fook, S. J.
Right arrow Articles by Kallok, M. J.

Journal of Applied Physiology, Vol 52, Issue 4 1000-1007, Copyright © 1982 by American Physiological Society

ARTICLES

Bronchial-arterial interdependence in isolated dog lung

S. J. Lai-Fook and M. J. Kallok

The bronchus and artery, embedded in the lung parenchyma, were modeled as adjoining cylindrical tubes in an elastic continuum. Solutions using finite-element analysis of nonuniform stress and strain occurring from an initial uniform state were computed for a reduction in arterial pressure. Maximal nonuniform principal and shear stresses in the parenchyma, equal to 2.5 times the mean periarterial stresses, occurred in the region adjacent to the bronchial-arterial joint. Bronchial cross section became oval and elongated along the line passing through the centers of the tubes, whereas arterial cross section elongated at right angles to this line. These predicted changes in shape of bronchus and artery were verified by radiographic measurements in isolated lobes, held at constant transpulmonary pressures of 4 and 25 cmH2O while arterial pressure was varied. Results suggest that peribronchovascular interstitial fluid pressure may be nonuniform and that the bronchial-arterial joint may be the preferential site for emphysematous perivascular lesions, which may occur on lung hyperinflation.


This article has been cited by other articles:


Home page
 Am. J. Respir. Crit. Care Med.Home page
N. E. Vlahakis and R. D. Hubmayr
Cellular Stress Failure in Ventilator-injured Lungs
Am. J. Respir. Crit. Care Med., June 15, 2005; 171(12): 1328 - 1342.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
M. Kotani, T. Kotani, Z. Li, R. Silbajoris, C.A. Piantadosi, and Y-C.T. Huang
Reduced inspiratory flow attenuates IL-8 release and MAPK activation of lung overstretch
Eur. Respir. J., August 1, 2004; 24(2): 238 - 246.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
R. H. Brown and W. Mitzner
Airway closure with high PEEP in vivo
J Appl Physiol, September 1, 2000; 89(3): 956 - 960.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online