Journal of Applied Physiology Journal of Applied Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 51: 941-947, 1981;
8750-7587/81 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Fuller, E. O.
Right arrow Articles by Nutter, D. O.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Fuller, E. O.
Right arrow Articles by Nutter, D. O.

Journal of Applied Physiology, Vol 51, Issue 4 941-947, Copyright © 1981 by American Physiological Society

ARTICLES

Endurance training in the rat. II. Performance of isolated and intact heart

E. O. Fuller and D. O. Nutter

The effects of isotonic physical training and detraining on cardiac function were studied in young and adult male rats trained by graded treadmill running and compared with sedentary controls. Absolute left ventricular mass was not increased, and ventricular compliance was not altered by training. Ventricular function curves that plotted peak systolic pressure, maximum rate of rise of left ventricular pressure, cardiac output, coronary flow, or stroke work as a function of atrial filling height in the isolated perfused heart did not demonstrate a training effect in either age group. The cardiac response to hypoxia was also comparable in the trained and sedentary rats. The base-line heart rate of anesthetized rats, in which in situ cardiac function was studied, was lower in the trained rats (321 +/- 14 vs. 377 +/- 8, P less than 0.005). Resting hemodynamics and left ventricular function curves generated from pressure-flow data during volume infusion did not differentiate between the hearts of trained and sedentary rats. In conclusion, a moderate level of endurance training did not enhance cardiac contractility when this was assessed under nonexercise conditions in both the isolated perfused heart and intact in situ heart preparations.


This article has been cited by other articles:


Home page
 J. Appl. Physiol.Home page
C. Reboul, S. Tanguy, J. M. Juan, M. Dauzat, and P. Obert
Cardiac remodeling and functional adaptations consecutive to altitude training in rats: implications for sea level aerobic performance
J Appl Physiol, January 1, 2005; 98(1): 83 - 92.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
G. M. Diffee and D. F. Nagle
Exercise training alters length dependence of contractile properties in rat myocardium
J Appl Physiol, March 1, 2003; 94(3): 1137 - 1144.
[Abstract] [Full Text] [PDF]

Home page
 Cardiovasc ResHome page
R.M Mohan, J.K Choate, S Golding, N Herring, B Casadei, and D.J Paterson
Peripheral pre-synaptic pathway reduces the heart rate response to sympathetic activation following exercise training: role of NO
Cardiovasc Res, July 1, 2000; 47(1): 90 - 98.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
B. M. Palmer, J. M. Lynch, S. M. Snyder, and R. L. Moore
Effects of chronic run training on Na+-dependent Ca2+ efflux from rat left ventricular myocytes
J Appl Physiol, February 1, 1999; 86(2): 584 - 591.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
S. K. Powers, H. A. Demirel, H. K. Vincent, J. S. Coombes, H. Naito, K. L. Hamilton, R. A. Shanely, and J. Jessup
Exercise training improves myocardial tolerance to in vivo ischemia-reperfusion in the rat
Am J Physiol Regulatory Integrative Comp Physiol, November 1, 1998; 275(5): R1468 - R1477.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online