Journal of Applied Physiology Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 51: 671-677, 1981;
8750-7587/81 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kinasewitz, G. T.
Right arrow Articles by Fishman, A. P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kinasewitz, G. T.
Right arrow Articles by Fishman, A. P.

Journal of Applied Physiology, Vol 51, Issue 3 671-677, Copyright © 1981 by American Physiological Society

ARTICLES

Influence of alterations in Starling forces on visceral pleural fluid movement

G. T. Kinasewitz and A. P. Fishman

The influence of alterations in hydrostatic and oncotic pressure gradients on fluid movement across the visceral pleura was examined in 16 spontaneously breathing anesthetized dogs. The left lung was enclosed in a water-impermeable polyethylene membrane, creating a visceral pleural space; visceral fluid movement was determined as the formation or reabsorption of fluid in this space. Aortic, pulmonary arterial, right and left atrial, and pleural pressures were monitored; oncotic pressure was calculated from the protein concentration of plasma and pleural fluid. Left atrial pressure was varied from 0 to 30 mmHg and pulmonary arterial pressure from 15 to 36 mmHg by inflating atrial balloon catheters; the plasma-to-pleural fluid oncotic gradient was varied from 6.8 to 19.3 mmHg by infusing saline. The movement of fluid across the visceral pleura was significantly (P less than 0.001) related to the effective (transmural hydrostatic pressure minus oncotic gradient) pulmonary arterial (r = 0.87) and left atrial pressures (r = 0.92). The filtration coefficient of the visceral pleura estimated by our technique was 1.1 x 10(-6) ml.s-1.cmH2O-1.cm-2. These results not only confirm the concept that fluid flux across the visceral pleura is determined by the action of Starling forces across this membrane but also provide an estimate of the filtration coefficient for the visceral pleura.


This article has been cited by other articles:


Home page
 Physiol. Rev.Home page
S. J. LAI-FOOK
Pleural Mechanics and Fluid Exchange
Physiol Rev, April 1, 2004; 84(2): 385 - 410.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
C. H. Hatzoglou, K. I. Gourgoulianis, and P. A. Molyvdas
Effects of SNP, ouabain, and amiloride on electrical potential profile of isolated sheep pleura
J Appl Physiol, April 1, 2001; 90(4): 1565 - 1569.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Cell Physiol.Home page
Y. Song, B. Yang, M. A. Matthay, T. Ma, and A. S. Verkman
Role of aquaporin water channels in pleural fluid dynamics
Am J Physiol Cell Physiol, December 1, 2000; 279(6): C1744 - C1750.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
A. A. Eid, J. I. Keddissi, and G. T. Kinasewitz
Hypoalbuminemia as a Cause of Pleural Effusions
Chest, April 1, 1999; 115(4): 1066 - 1069.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online