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J Appl Physiol 51: 520-523, 1981;
8750-7587/81 $5.00
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Journal of Applied Physiology, Vol 51, Issue 2 520-523, Copyright © 1981 by American Physiological Society

ARTICLES

Breath-to-breath monitoring of inspiratory occlusion pressures in humans

S. A. Ward, K. A. Agleh and C. S. Poon

A pneumatically drive occlusion device has been designed to implement brief (ca. 130 ms) inspiratory airway occlusion and to monitor the associated inspiratory occlusion pressure (P100) on a breath-to-breath basis in humans. The device, which has a low resistance when patent, provides no discernible modulation of ventilation during steady and nonsteady states of moderate intensity cycle-ergometer exercise. With this technique, it is possible to undertake investigations of dynamic as well as steady-state P100 responses to stimuli such as extensive, inhaled CO2, and hypoxia.


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