Journal of Applied Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 51: 33-39, 1981;
8750-7587/81 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Pimmel, R. L.
Right arrow Articles by Bromberg, P. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Pimmel, R. L.
Right arrow Articles by Bromberg, P. A.

Journal of Applied Physiology, Vol 51, Issue 1 33-39, Copyright © 1981 by American Physiological Society

ARTICLES

Correlation of airway resistance with forced random noise resistance parameters

R. L. Pimmel, J. M. Fullton, J. F. Ginsberg, M. J. Hazucha, E. D. Haak, W. F. McDonnell and P. A. Bromberg

The correlation between airway resistance (Raw) measured in a plethysmograph and three respiratory resistance parameters measured by forced random noise was evaluated. Forced random noise resistance parameters were the average resistance between 5 and 9 hz (R5-9), the average resistance between 20 and 24 Hz (R20-24), and the extrapolated resistance at 1 Hz (R1). We studied 22 healthy, nonsmoking subjects, 10 of whom had a history suggesting childhood asthma. Serial measurements were made after inhalation of aerosols containing increasing concentrations of methacholine of aerosols containing increasing concentrations of methacholine to obtain data in various stages of bronchoconstriction. There was a broad range of responsiveness to methacholine; the ratio of the peak to base-line values of Raw ranged from 1.1 to 6.3. R1, R5-9, and R20-24 were related to Raw by linear regression analysis. R1 and R5-9 showed excellent correlation with Raw (r = 093 and 4=0.91, respectively); R20-24 showed much poorer correlation (r = 0.62). The slopes of the regression equations for R1 and R5-9 were 1.56 and 0.51, respectively; thus neither provided an exact measure of Raw. The data appear to be consistent with a model in which most of the methacholine-induced increase in resistance occurred in the peripheral airways and only a small fraction in the central airway.


This article has been cited by other articles:


Home page
 Am. J. Respir. Crit. Care Med.Home page
C. DELACOURT, H. LORINO, C. FUHRMAN, M. HERVE-GUILLOT, P. REINERT, A. HARF, and B. HOUSSET
Comparison of the Forced Oscillation Technique and the Interrupter Technique for Assessing Airway Obstruction and Its Reversibility in Children
Am. J. Respir. Crit. Care Med., September 15, 2001; 164(6): 965 - 972.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
C. DELACOURT, H. LORINO, M. HERVE-GUILLOT, P. REINERT, A. HARF, and B. HOUSSET
Use of the Forced Oscillation Technique to Assess Airway Obstruction and Reversibility in Children
Am. J. Respir. Crit. Care Med., March 1, 2000; 161(3): 730 - 736.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online