Journal of Applied Physiology
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J Appl Physiol 51: 176-178, 1981;
8750-7587/81 $5.00
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Journal of Applied Physiology, Vol 51, Issue 1 176-178, Copyright © 1981 by American Physiological Society


ARTICLES

Reduced norepinephrine response to dynamic exercise in human subjects during O2 breathing

B. Hesse, I. L. Kanstrup, N. J. Christensen, T. Ingemann-Hansen, J. F. Hansen, J. Halkjaer-Kristensen and F. B. Petersen

The purpose of this investigation was to study the influence of hyperoxia on catecholamine response to dynamic exercise. While breathing either 21 or 100% O2 seven subjects performed submaximal bicycle exercise. Arterial blood pressure was similar in both exercise experiments. The CO2 output was not influenced by 100% O2 breathing, but increments in plasma lactate concentration were reduced. The increases in plasma norepinephrine and epinephrine concentrations and heart rate were significantly lower during 100% O2 than during 21% O2 breathing. The results suggest that O2 plays an important role in the regulation of sympathetic nervous activity during dynamic exercise in humans.


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