Journal of Applied Physiology
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J Appl Physiol 50: 320-324, 1981;
8750-7587/81 $5.00
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Journal of Applied Physiology, Vol 50, Issue 2 320-324, Copyright © 1981 by American Physiological Society

ARTICLES

Change in human blood plasma pH with pressure

E. Morild

For the first time, the effect of hydrostatic pressure on the pH in human blood plasma was determined under well-defined conditions. By means of a colorimetric method the change in plasma pH was examined from 1 to 1,500 bar (atm). The change was -2.5 x 10(-4).bar-1, and it is then established that this effect is unimportant for physiologically tolerable pressures. A discussion of the gas-liquid equilibrium of CO2 is included, with a short consideration of the pressure effect on the hemoglobin system.




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