Journal of Applied Physiology Journal of Applied Physiology
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J Appl Physiol 48: 868-871, 1980;
8750-7587/80 $5.00
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Journal of Applied Physiology, Vol 48, Issue 5 868-871, Copyright © 1980 by American Physiological Society


ARTICLES

beta-Adrenergic stimulation of respiratory ciliary activity

P. Verdugo, N. T. Johnson and P. Y. Tam

We investigated the effect of isoproterenol on ciliary activity using a mucus-free preparation of cultured ciliated cells of the rabbit trachea. The frequency of ciliary beating was monitored by dynamic laser-scattering spectroscopy. The results demonstrated that isoproterenol directly stimulates the activity of ciliated cells of the respiratory epithelium and that this effect is beta-adrenergic specific inasmuch as the observed stimulation can be blocked by propranolol.


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