Journal of Applied Physiology Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 48: 737-741, 1980;
8750-7587/80 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kanabus, E. W.
Right arrow Articles by Crawford, D. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kanabus, E. W.
Right arrow Articles by Crawford, D. W.

Journal of Applied Physiology, Vol 48, Issue 4 737-741, Copyright © 1980 by American Physiological Society

ARTICLES

Excursion of vibrating microelectrodes in tissue

E. W. Kanabus, C. Feldstein and D. W. Crawford

A vibrating microelectrode holder consisting of a support rod attached to the cone of a miniature loudspeaker facilitates electrode penetration into arterial wall tissue, eliminates surface dimpling, and relieves polarographic artifacts believed to be due to tissue compression. The longitudinal vibratory excursion of free microelectrode tips, measured with strobe illumination microscopy, varies from less than 0.9 to 137 micron depending on energizing voltage and frequency. Tissue penetration is achieved most effectively at the resonance frequency, about 200 Hz for the present system. Total tip excursion is not diminished when the electrode is penetrated into excised rabbit femoral artery, but tip motion relative to surrounding tissue is considerably attenuated because the arterial wall holds the electrode shaft rather firmly and follows its movements. This relative motion in tissue is only 2.7 +/- 0.8 micron at 200 Hz and 0.05 V and can be reduced further at higher frequencies without sacrificing the penetration advantages of the system. Thus under proper vibratory conditions microelectrodes can be easily inserted into the arterial wall with minimal tissue disturbance.


This article has been cited by other articles:


Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
S. M. Santilli, A. S. Tretinyak, and E. S. Lee
Transarterial wall oxygen gradients at the deployment site of an intra-arterial stent in the rabbit
Am J Physiol Heart Circ Physiol, October 1, 2000; 279(4): H1518 - H1525.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online