Journal of Applied Physiology Watch the video to learn how APS reaches out to developing nations.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 48: 500-504, 1980;
8750-7587/80 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Wilson, S. L.
Right arrow Articles by Abu-Osba, Y. K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Wilson, S. L.
Right arrow Articles by Abu-Osba, Y. K.

Journal of Applied Physiology, Vol 48, Issue 3 500-504, Copyright © 1980 by American Physiological Society

ARTICLES

Upper airway patency in the human infant: influence of airway pressure and posture

S. L. Wilson, B. T. Thach, R. T. Brouillette and Y. K. Abu-Osba

We have determined the influence of transmural pressure and neck posture on upper airway patency in infants after death. In natural resting postures, the airway was closed at transmural pressures not exceeding those normally seen during peak inspiratory airflow in the living infant, implying that a neuromuscular mechanism is necessary to maintain airway patency during life. Neck flexion raised closing pressure, making the airway more susceptible to collapse, whereas neck extension lowered closing pressure, making the airway more resistant to collapse. When the angle of flexion was kept constant, closing pressure was not significantly altered by turning the head or positioning the infant prone. Pressures above the corresponding closing pressure were required to reopen the closed airway, suggesting that the walls of the closed airway tended to adhere and implying that surface forces can impose an added load to airway-maintaining musculature during obstructive apnea in the living infant.


This article has been cited by other articles:


Home page
 Proc Am Thorac SocHome page
E. S. Katz and C. M. D'Ambrosio
Pathophysiology of Pediatric Obstructive Sleep Apnea
Proceedings of the ATS, February 15, 2008; 5(2): 253 - 262.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
K. P. Mason, D. Zurakowski, L. Connor, V. E. Karian, P. J. Fontaine, P. A. Sanborn, and P. E. Burrows
Infant Sedation for MR Imaging and CT: Oral versus Intravenous Pentobarbital
Radiology, December 1, 2004; 233(3): 723 - 728.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
C. L. Marcus, L. B. Fernandes Do Prado, J. Lutz, E. S. Katz, C. A. Black, P. Galster, and K. A. Carson
Developmental changes in upper airway dynamics
J Appl Physiol, July 1, 2004; 97(1): 98 - 108.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
S. Isono, A. Tanaka, Y. Tagaito, T. Ishikawa, and T. Nishino
Influences of head positions and bite opening on collapsibility of the passive pharynx
J Appl Physiol, July 1, 2004; 97(1): 339 - 346.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
J. P. Kirkness, P. R. Eastwood, I. Szollosi, P. R. Platt, J. R. Wheatley, T. C. Amis, and D. R. Hillman
Effect of surface tension of mucosal lining liquid on upper airway mechanics in anesthetized humans
J Appl Physiol, July 1, 2003; 95(1): 357 - 363.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
G. W. Don and K. A. Waters
Influence of sleep state on frequency of swallowing, apnea, and arousal in human infants
J Appl Physiol, June 1, 2003; 94(6): 2456 - 2464.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
ATS/ERS Statement on Respiratory Muscle Testing
Am. J. Respir. Crit. Care Med., August 15, 2002; 166(4): 518 - 624.
[Full Text] [PDF]

Home page
 Eur Respir JHome page
M.J. Morrell, Y. Arabi, B.R. Zahn, K.C. Meyer, J.B. Skatrud, and M. Safwan Badr
Effect of surfactant on pharyngeal mechanics in sleeping humans: implications for sleep apnoea
Eur. Respir. J., August 1, 2002; 20(2): 451 - 457.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
E. Verin, F. Series, C. Locher, C. Straus, M. Zelter, J.-P. Derenne, and T. Similowski
Effects of neck flexion and mouth opening on inspiratory flow dynamics in awake humans
J Appl Physiol, January 1, 2002; 92(1): 84 - 92.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
S. ISONO, A. TANAKA, T. ISHIKAWA, and T. NISHINO
Developmental Changes in Collapsibility of the Passive Pharynx during Infancy
Am. J. Respir. Crit. Care Med., September 1, 2000; 162(3): 832 - 836.
[Abstract] [Full Text]

Home page
 Arch. Dis. Child. Fetal Neonatal Ed.Home page
C. Morley
Continuous distending pressure
Arch. Dis. Child. Fetal Neonatal Ed., September 1, 1999; 81(2): 152F - 156.
[Full Text]

Home page
 J. Appl. Physiol.Home page
C. L. Marcus, J. Lutz, A. Hamer, P. L. Smith, and A. Schwartz
Developmental changes in response to subatmospheric pressure loading of the upper airway
J Appl Physiol, August 1, 1999; 87(2): 626 - 633.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
S. ISONO, A. SHIMADA, M. UTSUGI, A. KONNO, and T. NISHINO
Comparison of Static Mechanical Properties of the Passive Pharynx between Normal Children and Children with Sleep-disordered Breathing
Am. J. Respir. Crit. Care Med., April 1, 1998; 157(4): 1204 - 1212.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
T. Van Der Touw, A. B. H. Crawford, and J. R. Wheatley
Effects of a synthetic lung surfactant on pharyngeal patency in awake human subjects
J Appl Physiol, January 1, 1997; 82(1): 78 - 85.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online