Journal of Applied Physiology
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J Appl Physiol 47: 224-227, 1979;
8750-7587/79 $5.00
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Journal of Applied Physiology, Vol 47, Issue 1 224-227, Copyright © 1979 by American Physiological Society


ARTICLES

Subcutaneous tissue gas space pressure during superficial isobaric counterdiffusion

J. R. Cowley, C. Allegra and C. J. Lambertsen

Changes in subcutaneous tissue pressure caused by N2O-He, 1-ATA isobaric counterdiffusion gas phase development were measured. Only the ears of New Zealand White rabbits were subjected to counterdiffusion. The rabbits breathed a mixture of 80% N2O-20% O2 while their ears alone were surrounded by He and the rest of their bodies continued to be surrounded by air. Subcutaneous pressure changes were transmitted to the transducer-recorded system via a fluid-filled subcutaneous needle. When the gas phase developed in subcutaneous tissue, pressure rose and a maximum pressure (Pmax) was reached. Pmax in the counterdiffused ear was 48 +/- 10 (SD) Torr, and mean time to reach Pmax was 75 +/- 10 (SD) min. The findings are discussed in relation to the pathological processes of isobaric inert gas counterdiffusion.





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