| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Journal of Applied Physiology, Vol 46, Issue 3 451-456, Copyright © 1979 by American Physiological Society
ARTICLES |
L. Larsson, G. Grimby and J. Karlsson
Maximum values for isometric strength, dynamic strength, and speed of movement (MEV) in the quadriceps muscle were measured in 114 male subjects who were between 11 and 70 yr. Biopsy samples were taken from the quadriceps muscle in 51 of the subjects (22-65 yr. old). Isometric and dynamic strength increased up to the third decade, remained almost constant to the fifth decade, and then decreased with increasing age. However, no measurable external atrophy of the quadriceps muscle, explaining the decline in strength, could be seen in old age. Histochemical changes in the muscle tissue such as decreased proportion of type II fibers and a selective atrophy of type II fibers, were seen with increasing age. The strength decline in old age was also observed to correlate significantly with the type II fiber area. Multiple regression analyses indicated, however, that mechanisms other than the type II fiber atrophy might be responsible for the decline in strength performance during aging. The implications of these findings are discussed.
This article has been cited by other articles:
|
|
 |
|
  L. Cui, Y. Ju, L. Ding, M. Trejo-Morales, and I. M. Olfert Arteriolar and Venular Capillary Distribution in Skeletal Muscles of Old Rats J. Gerontol. A Biol. Sci. Med. Sci., September 1, 2008; 63(9): 928 - 935. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. A. Steinman Self-Reported Vision, Upper/Lower Limb Disability, and Fall Risk in Older Adults Journal of Applied Gerontology, August 1, 2008; 27(4): 406 - 423. [Abstract] [PDF]
|
|
|
|
 |
|
 D. Slivka, U. Raue, C. Hollon, K. Minchev, and S. Trappe Single muscle fiber adaptations to resistance training in old (>80 yr) men: evidence for limited skeletal muscle plasticity Am J Physiol Regulatory Integrative Comp Physiol, July 1, 2008; 295(1): R273 - R280. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Tanaka and D. R. Seals Endurance exercise performance in Masters athletes: age-associated changes and underlying physiological mechanisms J. Physiol., January 1, 2008; 586(1): 55 - 63. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. D. Hand, M. C. Kostek, R. E. Ferrell, M. J. Delmonico, L. W. Douglass, S. M. Roth, J. M. Hagberg, and B. F. Hurley Influence of promoter region variants of insulin-like growth factor pathway genes on the strength-training response of muscle phenotypes in older adults J Appl Physiol, November 1, 2007; 103(5): 1678 - 1687. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. T. Schroeder, C. Castaneda-Sceppa, Ying Wang, E. F. Binder, M. Kawakubo, Y. Stewart, T. Storer, R. Roubenoff, S. Bhasin, K. E. Yarasheski, et al. Hormonal regulators of muscle and metabolism in aging (HORMA): design and conduct of a complex, double masked multicenter trial Clinical Trials, October 1, 2007; 4(5): 560 - 571. [Abstract] [PDF]
|
|
|
|
 |
|
 B. K. Barry, M. A. Pascoe, M. Jesunathadas, and R. M. Enoka Rate Coding Is Compressed But Variability Is Unaltered for Motor Units in a Hand Muscle of Old Adults J Neurophysiol, May 1, 2007; 97(5): 3206 - 3218. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. H Host, D. R Sinacore, K. L Bohnert, K. Steger-May, M. Brown, and E. F Binder Training-Induced Strength and Functional Adaptations After Hip Fracture Physical Therapy, March 1, 2007; 87(3): 292 - 303. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. A. Knight and G. Kamen Modulation of motor unit firing rates during a complex sinusoidal force task in young and older adults J Appl Physiol, January 1, 2007; 102(1): 122 - 129. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. Katznelson, M. W Robinson, C. L Coyle, H. Lee, and C. E Farrell Effects of modest testosterone supplementation and exercise for 12 weeks on body composition and quality of life in elderly men Eur. J. Endocrinol., December 1, 2006; 155(6): 867 - 875. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Ahmadzadeh, D. Andreyev, E. A. Arriaga, and L. V. Thompson Capillary Electrophoresis Reveals Changes in Individual Mitochondrial Particles Associated With Skeletal Muscle Fiber Type and Age J. Gerontol. A Biol. Sci. Med. Sci., December 1, 2006; 61(12): 1211 - 1218. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. P. Marsh, M. E. Miller, A. M. Saikin, W. J. Rejeski, N. Hu, F. Lauretani, S. Bandinelli, J. M. Guralnik, and L. Ferrucci Lower Extremity Strength and Power Are Associated With 400-Meter Walk Time in Older Adults: The InCHIANTI Study J. Gerontol. A Biol. Sci. Med. Sci., November 1, 2006; 61(11): 1186 - 1193. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. H. Goodpaster, S. W. Park, T. B. Harris, S. B. Kritchevsky, M. Nevitt, A. V. Schwartz, E. M. Simonsick, F. A. Tylavsky, M. Visser, A. B. Newman, et al. The loss of skeletal muscle strength, mass, and quality in older adults: the health, aging and body composition study. J. Gerontol. A Biol. Sci. Med. Sci., October 1, 2006; 61(10): 1059 - 1064. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. T. Korhonen, A. Cristea, M. Alen, K. Hakkinen, S. Sipila, A. Mero, J. T. Viitasalo, L. Larsson, and H. Suominen Aging, muscle fiber type, and contractile function in sprint-trained athletes J Appl Physiol, September 1, 2006; 101(3): 906 - 917. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. P. Rader and J. A. Faulkner Effect of aging on the recovery following contraction-induced injury in muscles of female mice J Appl Physiol, September 1, 2006; 101(3): 887 - 892. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Liu-Ambrose, K. M. Khan, M. G. Donaldson, J. J. Eng, S. R. Lord, and H. A. McKay Falls-related self-efficacy is independently associated with balance and mobility in older women with low bone mass. J. Gerontol. A Biol. Sci. Med. Sci., August 1, 2006; 61(8): 832 - 838. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. F. Vallejo, E. T. Schroeder, L. Zheng, N. E. Jensky, and F. R. Sattler Cardiopulmonary responses to eccentric and concentric resistance exercise in older adults. Age Ageing, May 1, 2006; 35(3): 291 - 297. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. J. Woodhouse, A. Mukherjee, S. M. Shalet, and S. Ezzat The Influence of Growth Hormone Status on Physical Impairments, Functional Limitations, and Health-Related Quality of Life in Adults Endocr. Rev., May 1, 2006; 27(3): 287 - 317. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. E. Pistilli, P. M. Siu, and S. E. Alway Molecular regulation of apoptosis in fast plantaris muscles of aged rats. J. Gerontol. A Biol. Sci. Med. Sci., March 1, 2006; 61(3): 245 - 255. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. P. Rader and J. A. Faulkner Recovery from contraction-induced injury is impaired in weight-bearing muscles of old male mice J Appl Physiol, February 1, 2006; 100(2): 656 - 661. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D Q Xu, J X Li, Y Hong, and Y T Wang Effects of long term Tai Chi practice and jogging exercise on muscle strength and endurance in older people * Commentary Br. J. Sports Med., January 1, 2006; 40(1): 50 - 54. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Hatakenaka, H. Soeda, T. Okafuji, H. Yabuuchi, S. Shiokawa, J. Nishimura, and H. Honda Steroid Myopathy: Evaluation of Fiber Atrophy with T2 Relaxation Time--Rabbit and Human Study Radiology, December 21, 2005; (2005) 2381041720. [Abstract] [Full Text]
|
|
|
|
|
|
J. M. Kaufman and A. Vermeulen The Decline of Androgen Levels in Elderly Men and Its Clinical and Therapeutic Implications Endocr. Rev., October 1, 2005; 26(6): 833 - 876. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J.A.M Korfage, J.H. Koolstra, G.E.J. Langenbach, and T.M.G.J. van Eijden Fiber-type Composition of the Human Jaw Muscles--(Part 2) Role of Hybrid Fibers and Factors Responsible for Inter-individual Variation J. Dent. Res., September 1, 2005; 84(9): 784 - 793. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. I. Morse, J. M. Thom, N. D. Reeves, K. M. Birch, and M. V. Narici In vivo physiological cross-sectional area and specific force are reduced in the gastrocnemius of elderly men J Appl Physiol, September 1, 2005; 99(3): 1050 - 1055. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. R. Short, J. L. Vittone, M. L. Bigelow, D. N. Proctor, J. M. Coenen-Schimke, P. Rys, and K. S. Nair Changes in myosin heavy chain mRNA and protein expression in human skeletal muscle with age and endurance exercise training J Appl Physiol, July 1, 2005; 99(1): 95 - 102. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. G. Giresi, E. J. Stevenson, J. Theilhaber, A. Koncarevic, J. Parkington, R. A. Fielding, and S. C. Kandarian Identification of a molecular signature of sarcopenia Physiol Genomics, April 14, 2005; 21(2): 253 - 263. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. Dawson-Hughes The Role of Vitamin D in Fracture Prevention IBMS BoneKEy, April 1, 2005; 2(4): 6 - 10. [Full Text] [PDF]
|
|
|
|
|
|
E. Simoneau, A. Martin, and J. Van Hoecke Muscular Performances at the Ankle Joint in Young and Elderly Men J. Gerontol. A Biol. Sci. Med. Sci., April 1, 2005; 60(4): 439 - 447. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. C. Dreyer and E. Volpi Role of Protein and Amino Acids in the Pathophysiology and Treatment of Sarcopenia J. Am. Coll. Nutr., April 1, 2005; 24(2): 140S - 145S. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. T. Page, J. K. Amory, F. D. Bowman, B. D. Anawalt, A. M. Matsumoto, W. J. Bremner, and J. L. Tenover Exogenous Testosterone (T) Alone or with Finasteride Increases Physical Performance, Grip Strength, and Lean Body Mass in Older Men with Low Serum T J. Clin. Endocrinol. Metab., March 1, 2005; 90(3): 1502 - 1510. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. D. Veldhuis, J. N. Roemmich, E. J. Richmond, A. D. Rogol, J. C. Lovejoy, M. Sheffield-Moore, N. Mauras, and C. Y. Bowers Endocrine Control of Body Composition in Infancy, Childhood, and Puberty Endocr. Rev., February 1, 2005; 26(1): 114 - 146. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. R. Lanza, D. W. Russ, and J. A. Kent-Braun Age-related enhancement of fatigue resistance is evident in men during both isometric and dynamic tasks J Appl Physiol, September 1, 2004; 97(3): 967 - 975. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B Polla, G D'Antona, R Bottinelli, and C Reggiani Respiratory muscle fibres: specialisation and plasticity Thorax, September 1, 2004; 59(9): 808 - 817. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. K. Barry and R. G. Carson The Consequences of Resistance Training for Movement Control in Older Adults J. Gerontol. A Biol. Sci. Med. Sci., July 1, 2004; 59(7): M730 - M754. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. M. E. Franssen, R. Broekhuizen, P. P. Janssen, E. F. M. Wouters, and A. M. W. J. Schols Effects of Whole-Body Exercise Training on Body Composition and Functional Capacity in Normal-Weight Patients With COPD Chest, June 1, 2004; 125(6): 2021 - 2028. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. J. Pavol, E. F. Runtz, and Y.-C. Pai Young and Older Adults Exhibit Proactive and Reactive Adaptations to Repeated Slip Exposure J. Gerontol. A Biol. Sci. Med. Sci., May 1, 2004; 59(5): M494 - M502. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. C. Dean, A. D. Kuo, and N. B. Alexander Age-Related Changes in Maximal Hip Strength and Movement Speed J. Gerontol. A Biol. Sci. Med. Sci., March 1, 2004; 59(3): M286 - M292. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. R. Lanza, T. F. Towse, G. E. Caldwell, D. M. Wigmore, and J. A. Kent-Braun Effects of age on human muscle torque, velocity, and power in two muscle groups J Appl Physiol, December 1, 2003; 95(6): 2361 - 2369. [Abstract] [Full Text]
|
|
|
|
|
|
T. J. Doherty Invited Review: Aging and sarcopenia J Appl Physiol, October 1, 2003; 95(4): 1717 - 1727. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. J. Marcell Review Article: Sarcopenia: Causes, Consequences, and Preventions J. Gerontol. A Biol. Sci. Med. Sci., October 1, 2003; 58(10): M911 - 916. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Svensson, K. Stibrant Sunnerhagen, and G. Johannsson Five Years of Growth Hormone Replacement Therapy in Adults: Age- and Gender-Related Changes in Isometric and Isokinetic Muscle Strength J. Clin. Endocrinol. Metab., May 1, 2003; 88(5): 2061 - 2069. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Percheron, J.-Y. Hogrel, S. Denot-Ledunois, G. Fayet, F. Forette, E.-E. Baulieu, M. Fardeau, and J.-F. Marini Effect of 1-Year Oral Administration of Dehydroepiandrosterone to 60- to 80-Year-Old Individuals on Muscle Function and Cross-sectional Area: A Double-blind Placebo-Controlled Trial Arch Intern Med, March 24, 2003; 163(6): 720 - 727. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. J. Donato, K. Tench, D. H. Glueck, D. R. Seals, I. Eskurza, and H. Tanaka Declines in physiological functional capacity with age: a longitudinal study in peak swimming performance J Appl Physiol, February 1, 2003; 94(2): 764 - 769. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. A. Miszko, M. E. Cress, J. M. Slade, C. J. Covey, S. K. Agrawal, and C. E. Doerr Effect of Strength and Power Training on Physical Function in Community-Dwelling Older Adults J. Gerontol. A Biol. Sci. Med. Sci., February 1, 2003; 58(2): M171 - 175. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. J. Widrick, G. F. Maddalozzo, D. Lewis, B. A. Valentine, D. P. Garner, J. E. Stelzer, T. C. Shoepe, and C. M. Snow Morphological and Functional Characteristics of Skeletal Muscle Fibers From Hormone-replaced and Nonreplaced Postmenopausal Women J. Gerontol. A Biol. Sci. Med. Sci., January 1, 2003; 58(1): B3 - 10. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. A. Kent-Braun, A. V. Ng, J. W. Doyle, and T. F. Towse Human skeletal muscle responses vary with age and gender during fatigue due to incremental isometric exercise J Appl Physiol, November 1, 2002; 93(5): 1813 - 1823. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. A. Bua, S. H. McKiernan, J. Wanagat, D. McKenzie, and J. M. Aiken Mitochondrial abnormalities are more frequent in muscles undergoing sarcopenia J Appl Physiol, June 1, 2002; 92(6): 2617 - 2624. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. A. F. Singh Exercise Comes of Age: Rationale and Recommendations for a Geriatric Exercise Prescription J. Gerontol. A Biol. Sci. Med. Sci., May 1, 2002; 57(5): M262 - 282. [Full Text]
|
|
|
|
 |
|
 H.R. Gosker, H. van Mameren, P.J. van Dijk, M.P.K.J. Engelen, G.J. van der Vusse, E.F.M. Wouters, and A.M.W.J. Schols Skeletal muscle fibre-type shifting and metabolic profile in patients with chronic obstructive pulmonary disease Eur. Respir. J., April 1, 2002; 19(4): 617 - 625. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. L. Tracy and R. M. Enoka Older adults are less steady during submaximal isometric contractions with the knee extensor muscles J Appl Physiol, March 1, 2002; 92(3): 1004 - 1012. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. M. Matsumoto Andropause: Clinical Implications of the Decline in Serum Testosterone Levels With Aging in Men J. Gerontol. A Biol. Sci. Med. Sci., February 1, 2002; 57(2): M76 - 99. [Full Text]
|
|
|
|
|
|
M. Zamboni, E. Zoico, P. Tosoni, A. Zivelonghi, A. Bortolani, S. Maggi, V. Di Francesco, and O. Bosello Relation Between Vitamin D, Physical Performance, and Disability in Elderly Persons J. Gerontol. A Biol. Sci. Med. Sci., January 1, 2002; 57(1): M7 - 11. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Kerner, P. J. Turkaly, P. E. Minkler, and C. L. Hoppel Aging skeletal muscle mitochondria in the rat: decreased uncoupling protein-3 content Am J Physiol Endocrinol Metab, November 1, 2001; 281(5): E1054 - E1062. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Hulthen, B.-A. Bengtsson, K. S. Sunnerhagen, L. Hallberg, G. Grimby, and G. Johannsson GH Is Needed for the Maturation of Muscle Mass and Strength in Adolescents J. Clin. Endocrinol. Metab., October 1, 2001; 86(10): 4765 - 4770. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. A. Landers, G. R. Hunter, C. J. Wetzstein, M. M. Bamman, and R. L. Weinsier The Interrelationship Among Muscle Mass, Strength, and the Ability to Perform Physical Tasks of Daily Living in Younger and Older Women J. Gerontol. A Biol. Sci. Med. Sci., October 1, 2001; 56(10): B443 - 448. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. R. Thomas The Critical Link Between Health-Related Quality of Life and Age-Related Changes in Physical Activity and Nutrition J. Gerontol. A Biol. Sci. Med. Sci., October 1, 2001; 56(10): M599 - 602. [Full Text] [PDF]
|
|
|
|
|
|
I. S. Kwon, S. Oldaker, M. Schrager, L. A. Talbot, J. L. Fozard, and E. J. Metter Relationship Between Muscle Strength and the Time Taken to Complete a Standardized Walk-Turn-Walk Test J. Gerontol. A Biol. Sci. Med. Sci., September 1, 2001; 56(9): B398 - 404. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Trappe, M. Godard, P. Gallagher, C. Carroll, G. Rowden, and D. Porter Resistance training improves single muscle fiber contractile function in older women Am J Physiol Cell Physiol, August 1, 2001; 281(2): C398 - C406. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. W. Olanow, R. L. Watts, and W. C. Koller An algorithm (decision tree) for the management of Parkinson's disease (2001):: Treatment Neurology, June 12, 2001; 56(suppl_5): S1 - S88. [Full Text] [PDF]
|
|
|
|
