Journal of Applied Physiology Watch the video to see how APS reaches out to developing nations.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 45: 742-746, 1978;
8750-7587/78 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kendig, J. J.
Right arrow Articles by Cohen, E. N.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kendig, J. J.
Right arrow Articles by Cohen, E. N.

Journal of Applied Physiology, Vol 45, Issue 5 742-746, Copyright © 1978 by American Physiological Society

ARTICLES

Pressure, temperature, and repetitive impulse generation in crustacean axons

J. J. Kendig, T. M. Schneider and E. N. Cohen

Increases in nerve axon excitability, including repetitive activity, have from time to time been reported in nerves subjected to high hydrostatic pressure. With the description of the high-pressure nervous syndrome (HPNS) in human divers and experimental animals, this phenomenon is of interest as a possible basis for the hyperexcitability associated with HPNS. The present study was designed to define the relationships between temperature, pressure, and repetitive activity in isolated crayfish axons. Crayfish claw nerves were exposed to helium pressures between 1 and 200 atmospheres absolute (ATA) in a temperature-controlled recording chamber. Repetitive and spontaneous impulses were reliably evoked on compression. The probability of repetitive response was increased by low temperature and high pressure; the frequency of the repetitive activity was increased by high temperature and pressure. Repetitive activity appeared spontaneously in the unstimulated preparation but could be entrained by the stimulus. The results are consistent with a mechanism involving changes in nerve membrane lipid fluidity and in the time course of membrane ionic channel state changes, including those involved in repolarization and accommodation.


This article has been cited by other articles:


Home page
 J. Appl. Physiol.Home page
D. K. Mulkey, R. A. Henderson III, R. W. Putnam, and J. B. Dean
Pressure (4 ATA) increases membrane conductance and firing rate in the rat solitary complex</STRONG><BR> J Appl Physiol, September 1, 2003; 95(3): 922 - 930. <BR> <A HREF=[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online