Journal of Applied Physiology AJP: Heart and Circulatory Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 45: 495-501, 1978;
8750-7587/78 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Bishop, B.
Right arrow Articles by Thursby, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bishop, B.
Right arrow Articles by Thursby, M.

Journal of Applied Physiology, Vol 45, Issue 4 495-501, Copyright © 1978 by American Physiological Society

ARTICLES

Volume, flow, and timing of each breath during positive-pressure breathing in man

B. Bishop, J. Hirsch and M. Thursby

This study is a breath-by-breath analysis of the effects of 5, 10, and 15 cmH2O positive-pressure breathing (PPB) on man's steady-state breathing pattern. Inspiratory (TI), expiratory (TE), and cycle (TT) durations, tidal volumes (VT), minute ventilation (VE), mean inspiratory flow rate (VT/TI), and mean expiratory flow rate (VT/TE) were determined from pneumotachograph and Wedge spirometer recordings before and during steady states on PPB. End-tidal CO2 was continuously recorded. Seventeen adults, seated in a full body-box, breathed quietly for 8 min through a mouthpiece on a bag-in-box. Pressure in the body-box was lowered to the desired level prior to 4 min of stress. On all pressure levels, end-expiratory volume, VT, VE, VT/TI, and VT/TE increased; end-tidal CO2, TE, and TT decreased with no consistent change in TI. Calculated alveolar ventilations indicated that the increases in VE were true hyperventilations. Each individual increased VE by using a unique combination of VT, TI, and TE. End-expiratory volume increased less and expiratory flow increased more than would occur passively. Hence, it is concluded that active reflexes account for the resistance of the systems to the passive distention, the facilitation of expiratory flow, and the shortening of TE.


This article has been cited by other articles:


Home page
 J. Appl. Physiol.Home page
A. Vovk and A. P. Binks
Raising end-expiratory volume relieves air hunger in mechanically ventilated healthy adults
J Appl Physiol, September 1, 2007; 103(3): 779 - 786.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
M. Wysocki and M. Antonelli
Noninvasive mechanical ventilation in acute hypoxaemic respiratory failure
Eur. Respir. J., July 1, 2001; 18(1): 209 - 220.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online