Journal of Applied Physiology, Vol 45, Issue 2 177-181, Copyright © 1978 by American Physiological Society
Effects of physical training and lean body mass of plasma amino acids in man
G. Holm, L. Sullivan, R. Jagenburg and P. Bjorntorp
Postabsorptive plasma amino acid and insulin concentrations were determined
in subjects with hyperplastic obesity and in nonobese controls before and
after a 6-wk period of physical training. After the training period the
plasma concentrations of insulin and leucine decreased and the
concentration of alanine increased in the obese subjects. No changes were
noticed in the controls. The obese subjects had elevated plasma levels of
valine, isoleucine, leucine, tyrosine, and phenylalanine before as well as
after physical training. The concentrations of these amino acids were
correlated to the plasma insulin level and to lean body mass before but
only to lean body mass after physical training. It is suggested that the
lean body mass, whick is higher in hyperplastic obesity, contributes to the
elevated concentrations of amino acids, and it is unlikely that the insulin
decreases in the obese subjects after physical training is mediated through
an effect of amino acids on insulin secretion.
