Journal of Applied Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 44: 156-165, 1978;
8750-7587/78 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Mead, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mead, J.

Journal of Applied Physiology, Vol 44, Issue 2 156-165, Copyright © 1978 by American Physiological Society

ARTICLES

Analysis of the configuration of maximum expiratory flow-volume curves

J. Mead

The ratios of the instantaneous tangent slopes to corresponding chord slopes are sensitive to curvatures of flow-volume curves; and these dimensionless slope ratios, SR, plotted against fractional volumes remaining to be expired, VCf, are sensitive to the shape of flow-volume curves but insenitive to flow or volume magnitudes. SR-VCf curves predicted for lungs which empty homogeneously differ substantially from those predicted for lungs which empty nonhomogeneously, the latter showing systematic increases in SR with VCf which may extend beyond the homogeneous range. SR-VCf curves for some 80 healthy subjects show systematic changes with age (range 6-64 yr), but all are consistent with advanced obstructive lung disease (chronic bronchitis, emphysema, asthma) are consistent with nonhomogeneous emptying, but it does not seem likely that SR-VCf curves will prove useful for detecting early stages of disease.


This article has been cited by other articles:


Home page
 J. Appl. Physiol.Home page
S. Montmerle, J. Spaak, and D. Linnarsson
Lung function during and after prolonged head-down bed rest
J Appl Physiol, January 1, 2002; 92(1): 75 - 83.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
C. H. Liu, S. C. Niranjan, J. W. Clark Jr., K. Y. San, J. B. Zwischenberger, and A. Bidani
Airway mechanics, gas exchange, and blood flow in a nonlinear model of the normal human lung
J Appl Physiol, April 1, 1998; 84(4): 1447 - 1469.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online