Journal of Applied Physiology
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J Appl Physiol 44: 93-96, 1978;
8750-7587/78 $5.00
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Journal of Applied Physiology, Vol 44, Issue 1 93-96, Copyright © 1978 by American Physiological Society

ARTICLES

Changes in arterial blood gas tensions during unsteady-state exercise

I. H. Young and A. J. Woolcock

Arterial oxygen (Pao2) and carbon dioxide (Paco2) tensions and inspired minute ventilation were measured during the first 2 min of stair-climbing exercise in nine normal subjects. The subjects climbed a staircase at a rate of approximately 9 m vertical height every minute and arterial blood was drawn from an indwelling cannula at 15-s intervals. Large falls in Pao2 from a resting value of 92 +/- 2.0 (mean +/- SE) Torr to a lowest value of 65 +/- 3.4 Torr were recorded in the first 50 s of exercise while Paco2 oscillated around the resting value. Most subjects demonstrated an initial plateau of Pao2 for at least 7 s followed by a rapid fall and subsequent rise toward the resting level after 1 min. The falls in Pao2 measured were larger than those reported for laboratory exercise. The possible reasons for this discrepancy are discussed.


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W. Wagner Jr, L. Latham, M. Gillespie, J. Guenther, and R. Capen
Direct measurement of pulmonary capillary transit times
Science, October 22, 1982; 218(4570): 379 - 381.
[Abstract] [PDF]


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