Journal of Applied Physiology
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J Appl Physiol 42: 650-655, 1977;
8750-7587/77 $5.00
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Journal of Applied Physiology, Vol 42, Issue 4 650-655, Copyright © 1977 by American Physiological Society

ARTICLES

A modified forced oscillation technique for measurements of respiratory resistance

H. Aronsson, L. Solymar, J. Dempsey, J. Bjure, T. Olsson and B. Bake

We present a modification of forced oscillation technique for automated determination of total respiratory resistance during inspiration. The modifications consist of a computerized signal averaging and an optimization technique in the assessment of the resistance value. Thereby a favorable signal-to-noise ratio is obtained, allowing very low superimposed pressure oscillations. The method is validated by comparison with a conventional esophageal balloon method, by estimating added mechanical resistances in healthy subjects and by measuring the effect of bronchodilation in asthmatic children. The coefficient of variation as obtained from day-to-day measurements was about 7%. Mechanical resistances, estimated as the difference in total resistance with and without external resistance, were within 7% of their values determined for the resistances alone. A significant decrease in resistance was obtained in each of the asthmatic children following bronchodilation.


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