Journal of Applied Physiology, Vol 41, Issue 6 826-831, Copyright © 1976 by American Physiological Society

ARTICLES

Interactions between local and reflex influences on human forearm skin blood flow

J. M. Johnson, G. L. Brengelmann and L. B. Rowell

A three-part experiment was designed to examine interactions between local and reflex influences on forearm skin blood flow (SkBF). In part I locally increasing arm skin temperature (Tsk) to 42.5 degrees C was not associated with increases in underlying forearm muscle blood flow, esophageal temperature (Tes), or forearm blood flow in the contralateral cool arm. In part II whole-body Tsk was held at 38 or 40 degrees C and the surface temperature of one arm held at 38 or 42 degrees C for prolonged periods. SkBF in the heated arm rose rapidly with the elevation in body Tsk and arm Tsk continued to rise as Tes rose. SkBF in the arm kept at 32 degrees C paralleled rising Tes. In six studies, SkBF in the cool arm ultimately converged with SkBF in the heated arm. In eight other studies, heated arm SkBF maintained an offset above cool arm SkBF throughout the period of whole-body heating. In part III, local arm Tsk of 42.5 degrees C did not abolish skin vasoconstrictor response to lower body negative pressure. We conclude that local and reflex influences to skin interact so as to modify the degree but not the pattern of skin vasomotor response.

This article has been cited by other articles:

				D. A. Low, M. Shibasaki, S. L. Davis, D. M. Keller, and C. G. Crandall Does local heating-induced nitric oxide production attenuate vasoconstrictor responsiveness to lower body negative pressure in human skin? J Appl Physiol, May 1, 2007; 102(5): 1839 - 1843. [Abstract] [Full Text] [PDF]

				F. Yamazaki, R. Sone, K. Zhao, G. E. Alvarez, W. A. Kosiba, and J. M. Johnson Rate dependency and role of nitric oxide in the vascular response to direct cooling in human skin J Appl Physiol, January 1, 2006; 100(1): 42 - 50. [Abstract] [Full Text] [PDF]

				S. L. Davis, P. J. Fadel, J. Cui, G. D. Thomas, and C. G. Crandall Skin blood flow influences near-infrared spectroscopy-derived measurements of tissue oxygenation during heat stress J Appl Physiol, January 1, 2006; 100(1): 221 - 224. [Abstract] [Full Text] [PDF]

				J. Cui, A. Arbab-Zadeh, A. Prasad, S. Durand, B. D. Levine, and C. G. Crandall Effects of Heat Stress on Thermoregulatory Responses in Congestive Heart Failure Patients Circulation, October 11, 2005; 112(15): 2286 - 2292. [Abstract] [Full Text] [PDF]

				T. A. Munce and W. L. Kenney Age-specific modification of local cutaneous vasodilation by capsaicin-sensitive primary afferents J Appl Physiol, September 1, 2003; 95(3): 1016 - 1024. [Abstract] [Full Text] [PDF]

				K. G Baker, V. J Robertson, and F. A Duck A Review of Therapeutic Ultrasound: Biophysical Effects Physical Therapy, July 1, 2001; 81(7): 1351 - 1358. [Abstract] [Full Text] [PDF]

				N. Charkoudian, B. Fromy, and J.-L. Saumet Reflex control of the cutaneous circulation after acute and chronic local capsaicin J Appl Physiol, May 1, 2001; 90(5): 1860 - 1864. [Abstract] [Full Text] [PDF]

				G. Ferretti ; and S. Koga Letters to the Editor J Appl Physiol, October 1, 1998; 85(4): 1593 - 1600. [Abstract] [Full Text] [PDF]

				E. M. Brooks-Asplund and W. L. Kenney Chronic hormone replacement therapy does not alter resting or maximal skin blood flow J Appl Physiol, August 1, 1998; 85(2): 505 - 510. [Abstract] [Full Text] [PDF]

				C. T. Minson, S. L. Wladkowski, A. F. Cardell, J. A. Pawelczyk, and W. L. Kenney Age alters the cardiovascular response to direct passive heating J Appl Physiol, April 1, 1998; 84(4): 1323 - 1332. [Abstract] [Full Text] [PDF]

				C. A. Ray, K. M. Hume, K. H. Gracey, and E. T. Mahoney Muscle cooling delays activation of the muscle metaboreflex in humans Am J Physiol Heart Circ Physiol, November 1, 1997; 273(5): H2436 - H2441. [Abstract] [Full Text] [PDF]

				C. A. Ray and K. H. Gracey Augmentation of exercise-induced muscle sympathetic nerve activity during muscle heating J Appl Physiol, June 1, 1997; 82(6): 1719 - 1733. [Abstract] [Full Text] [PDF]

				E. Picano, R. Testa, M. Pogliani, F. Lattanzi, V. Gaudio, and A. L'Abbate Increase of Walking Capacity After Acute Aminophylline Administration in Intermittent Claudication Angiology, December 1, 1989; 40(12): 1035 - 1039. [Abstract] [PDF]