Journal of Applied Physiology Watch the video to see how APS reaches out to developing nations.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 41: 153-158, 1976;
8750-7587/76 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Wellman, J. J.
Right arrow Articles by McFadden, E. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Wellman, J. J.
Right arrow Articles by McFadden, E. R., Jr

Journal of Applied Physiology, Vol 41, Issue 2 153-158, Copyright © 1976 by American Physiological Society

ARTICLES

Effect of volume history on successive partial expiratory flow-volume maneuvers

J. J. Wellman, R. Brown, R. H. Ingram Jr, J. Mead and E. R. McFadden Jr

In normal subjects, the second of two successive partial expiratory flow-volume (PEFV 2) curves often had higher isovolume maximal expiratory flow rates (Vmax) than the first (PEFV 1) (mean increase 30.2 +/- 13%). The higher Vmax on PEFV 2 was present only when there was a greater lung elastic recoil pressure (Pst(L)). In eight subjects the Pst(L) derived from sequential partial quasi-static pressure-volume curves, from interruption of the flow-volume maneuvers and at the start of the PEFV curves showed that isovolume upstream resistance increased although Vmax also increased after going to residual volume (RV). In four subjects the RV volume history did not change the pressure flow relationship across the upstream airways. If airways dimensions were the sole determinant of Vmax, then Vmax on PEFV 2 would be the same or smaller than on PEFV 1. That the opposite was observed in our study indicates that the increase in Pst(L), which results from parenchymal hysteresis, offsets any dimensional decrease in upstream airways due to airways hysteresis.


This article has been cited by other articles:


Home page
 J. Appl. Physiol.Home page
J. H. T. Bates, A. Cojocaru, and L. K. A. Lundblad
Bronchodilatory effect of deep inspiration on the dynamics of bronchoconstriction in mice
J Appl Physiol, November 1, 2007; 103(5): 1696 - 1705.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
P. M. A. Calverley and N. G. Koulouris
Flow limitation and dynamic hyperinflation: key concepts in modern respiratory physiology
Eur. Respir. J., January 1, 2005; 25(1): 186 - 199.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
G. E. TZELEPIS, S. ZAKYNTHINOS, T. VASSILAKOPOULOS, S. GEROULANOS, and C. ROUSSOS
Inspiratory Maneuver Effects on Peak Expiratory Flow . Role of Lung Elastic Recoil and Expiratory Pressure
Am. J. Respir. Crit. Care Med., November 1, 1997; 156(5): 1399 - 1404.
[Abstract] [Full Text]

Home page
 J. Appl. Physiol.Home page
J. R. Rodarte
Invited Editorial on "Detection of expiratory flow limitation during exercise in COPD patients"
J Appl Physiol, March 1, 1997; 82(3): 721 - 722.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
N. G. Koulouris, I. Dimopoulou, P. Valta, R. Finkelstein, M. G. Cosio, and J. Milic-Emili
Detection of expiratory flow limitation during exercise in COPD patients
J Appl Physiol, March 1, 1997; 82(3): 723 - 731.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online