Journal of Applied Physiology, Vol 40, Issue 5 815-818, Copyright © 1976 by American Physiological Society
Solubility of 92 in blood with different hemoglobin concentrations at low temperatures
C. Christoforides and J. Hedley-Whyte
The Brunsen solubility coefficients for O2 in blood obtained from healthy
nonsmoking subjects have been determined at 0, 6, and 12 degrees C for
bloods of hemoglobin concentrations 5.6, 10.2, 15.7, and 22.5 g/100 ml.
Direct gasometric measurements show that blood has a relative solubility
(alphabeta/alphah2o) different for each hemoglobin concentration but
constant for any given hemoglobin concentration at the temperatures studied
(0.6, and 12 degrees C). For hemoglobin concentrations 5.6, 10.2, 15.7, and
22.5 g/100 ml alphabetao degrees C/alphabeta 12 degrees C rations were
1.36, 1.35, 1.35, and 1.35, respectively. The alpha H20(0 degrees C)/alpha
H20(12 degrees C) ratio is 1.34. Consequently, it was possible to construct
a table for the Brunsen solubility coefficients for O2 in blood from O to
15 degrees C of different hemoglobulin concentrations. Values from 10 to 15
degrees C published in the Biologal Hanbook, Respiration and Circulation,
based on extrapolations from previous direct measurements of temperatures
from 18 to 37 degrees C differ only 1% from our present results.
