Journal of Applied Physiology
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J Appl Physiol 40: 644-647, 1976;
8750-7587/76 $5.00
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Journal of Applied Physiology, Vol 40, Issue 4 644-647, Copyright © 1976 by American Physiological Society

ARTICLES

Polymer membrane sensors for continuous intravascular monitoring of blood pH

O. H. LeBlanc, J. F. Brown Jr, J. F. klebe, L. W. Niedrach, G. M. Slusarczuk and W. H. Stoddard Jr

A new type of pH sensor suitable for chronic intra-vascular implantation by virtue of its small size, flexibility, and ruggedness was constructed and evaluated. The pH-sensitive element was a thin film of an elastromeric polymer made ion permselective to proteons by adding a lipophilic, specific H+-ion carrier. This was coated onto small diameter silver wires to form sensors. In preliminary trials in anesthetized dogs, the sensors permitted continuous, accurate in vivo blood pH measurement with rapid response (less than 0.1 s).


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