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J Appl Physiol 40: 247-249, 2005;
8750-7587/05 $8.00
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Collection of normal canine tracheobronchial secretions

G. K. Adams 1, E. F. Aharonson 1, M. J. Reasor 1, and D. F. Proctor 1

1 Department of Environmental Medicine, The Johns Hopkins University School of Hygiene and Public Health, Baltimore, Maryland 21205

A technique is described for the collection of tracheobronchial secretions from the upper trachea of anesthetized dogs. The method is simple, relatively quantitative, and provides secretory material in quantity suitable for biochemical or rheological studies. In 42 experiments comprising 184 individual samples we have found the collection rate of tracheobronchial secretions to be 1.0 ± 0.1 mg/min per kg (mean ± SEM).

airway mucus; trachea; anesthetized dogs

Submitted on June 11, 1975






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