Journal of Applied Physiology Virginia Commonwealth University
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Appl Physiol 39: 916-919, 1975;
8750-7587/75 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Drazen, J. M.
Right arrow Articles by Austen, K. F.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Drazen, J. M.
Right arrow Articles by Austen, K. F.

Journal of Applied Physiology, Vol 39, Issue 6 916-919, Copyright © 1975 by American Physiological Society

ARTICLES

Pulmonary response to antigen infusion in the sensitized guinea pig: modification by atropine

J. M. Drazen and K. F. Austen

Alterations in pulmonary conductance, dynamic compliance, respiratory frequency, minute volume, mean arterial pressure, pulse rate, relaxation volume-to-dry weight ratio, and wet-to-dry weight ratio resulting from antigen infusion in sensitized guinea pigs was examined with and without atropine treatment. In untreated animals 3 min after antigen infusion there were significant decreases in dynamic compliance and pulmonary conductance with an increase in relaxation volume-to-dry weight ratio while other parameters were not altered. In atropine-treated animals antigen infusion resulted in a decreased dynamic compliance and an increased relaxation volume-to-dry weight ratio but no significant change in pulmonary conductance. This suggests that the alterations in large and central airway tone resulting from antigen infusion are mediated predominantly by secondary cholinergic mechanisms while peripheral airway effects are mainly noncholinergic.


This article has been cited by other articles:


Home page
 J. Appl. Physiol.Home page
B. J. Canning
Reflex regulation of airway smooth muscle tone
J Appl Physiol, September 1, 2006; 101(3): 971 - 985.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
D. L. Kellogg Jr., S. R. Morris, S. B. Rodriguez, Y. Liu, M. Grossmann, G. Stagni, and A. M. M. Shepherd
Thermoregulatory reflexes and cutaneous active vasodilation during heat stress in hypertensive humans
J Appl Physiol, July 1, 1998; 85(1): 175 - 180.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online