Journal of Applied Physiology, Vol 39, Issue 2 337-340, Copyright © 1975 by American Physiological Society
Hypothermia and rewarming induced by surface and He-O2 inhalate temperature control
A. V. Beran, K. G. Proctor and D. R. Sperling
Hypothermia and rewarming were induced by a combination of
temperature-controlled surface and inhalate methods in rabbits. To
facilitate respiratory heat exchange, inhalate-respiratory tract
temperature and humidity gradients and thermal conductivity were increased.
In addition, the upper respiratory tract was bypassed by an endotracheal
tube. To aid in maintaining satisfactory circulatory dynamics, hypercapnia
and hypoxia were induced. The combined surface and inhalate method produced
a markedly more effective rate of cooling than surface
temperature-controlled method alone. Animals survived core temperatures as
low as 20.9 degrees C with no complications. The noninvasive simplicity of
this method suggests its potential applicability in many clinical
situations.
